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Background: Vibrio cholerae are oxidase-positive bacteria that are classified into various serotypes based on the O surface antigen. V. cholerae serotypes are divided into two main groups: the O1 and O139 group and the non-O1/non-O139 group. O1 and O139 V. cholerae are related to cholera infection, whereas non-O1/non-O139 V. cholerae (NOVC) can cause cholera-like diarrhea. A PubMed search revealed that only 16 cases of necrotizing fasciitis caused by NOVC have been recorded in the scientific literature to date. We report the case of a Japanese woman who developed necrotizing fasciitis caused by NOVC after traveling to Taiwan and returning to Japan., Case Presentation: A 63-year-old woman visited our hospital because she had experienced left knee pain for the past 3 days. She had a history of colon cancer (Stage IV: T3N3 M1a) and had received chemotherapy. She had visited Taiwan 5 days previously, where she had received a massage. She was diagnosed with septic shock owing to necrotizing fasciitis. She underwent fasciotomy and received intensive care. She recovered from the septic shock; however, after 3 weeks, she required an above-knee amputation for necrosis and infection. Her condition improved, and she was discharged after 22 weeks in the hospital., Conclusions: With the increase in tourism, it is important for clinicians to check patients' travel history. Clinicians should be alert to the possibility of necrotizing fasciitis in patients with risk factors. Necrotizing fasciitis caused by NOVC is severe and requires early fasciotomy and debridement followed by intensive postoperative care.

Yersinia was isolated from imported raw meat and fowl products by HeLa cell treatment and conventional KOH-treatment, to obtain information on the origin of pathogenic Yersinia in Japan. Forty-one strains of Yersinia enterocolitica and one strain of Yersinia pseudotuberculosis, serotype 4b were isolated from 38 (3.0%) of 1278 samples of pork, two (0.3%) of 612 samples of beef and two (0.3%) of 615 samples of chicken. Y. enterocolitica isolates belonged to B:4/O:3 (biotype/serotype, 15 strains), B:3/O:3 (two strains) and B:3 variant/O:3 (17 strains) and B:3/O:5.27 (seven strains). The B:4/O:3 which is globally prevalent among humans and animals was isolated from pork samples from Denmark and the US and from beef samples from Australia, the B:3/O:3 from pork samples from Canada, the B:3 variant/O:3 from pork samples from Taiwan and from chicken samples from Thailand, the B:3/O:5.27 from pork samples from the US and Taiwan and Y. pseudotuberculosis, serotype 4b from pork samples from Canada. These findings suggest that pathogenic Y. enterocolitica strains can be introduced into Japan by the import of pork from pig producing countries. The HeLa cell treatment was found to be superior to the conventional method.