A recent study conducted at China Medical University in Taichung, Taiwan, has found that Coenzyme Q0 (CoQ0), a derivative from Antrodia camphorata, has anti-melanogenic, anti-photoaging, and anti-inflammatory effects on keratinocyte cells. The researchers discovered that CoQ0 activates Nrf2-mediated antioxidant pathways, downregulates alpha-MSH expression, and inhibits melanogenesis and melanin generation. Additionally, CoQ0 enhances Nrf2 nuclear translocation, resulting in antioxidant expression and the inhibition of ROS-mediated inflammation. The study suggests that CoQ0 could be used in topical cosmetic applications. [Extracted from the article]