1. Preoperative Counts of CD4 T-lymphocytes and Early Postoperative Infective Complications in HIV-positive Patients.
- Author
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Savioz, D., Chilcott, M., Ludwig, C., Savioz, M., Kaiser, L., Leissing, C., Bühler, L., Peter, R., and Morel, Ph.
- Subjects
HIV-positive persons ,CD4 antigen ,SURGICAL complications - Abstract
Objective: To assess the relationship between postoperative infective complications and the CD4 count. Design: Retrospective and biometric study. Setting: Two university hospitals, Switzerland. Subject: 40 HIV-positive patients who had had CD4 counts done during the three months before operation. Interventions: Clean and contaminated gastrointestinal and orthopaedic procedures. Main outcome measure: Postoperative infective complications. Results: 15 patients developed postoperative infective complications (38%), 6 of which (40%) were HIV-related. CD4 cell count, as well as the type of operation (contaminated or clean), influenced the infective complication rate. The risk of infective complications after a contaminated procedure when the CD4 count was below 200 mm[sup 3] was more than 50%. In clean operations, even when the CD4 cell count was close to 0, the rate of infective complications was never as high as 50%. Patients with a CD4 cell count of 500 or more have a similar rate of infective complications as HIV seronegative patients. Conclusion: Indications for operation in HIV-positive patients must take into account the CD4 cell count and the type of operation. [ABSTRACT FROM AUTHOR]
- Published
- 1998
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