1. Improvement of arterial oxygenation in free-ranging moose (Alces alces) immobilized with etorphine-acepromazine-xylazine.
- Author
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Lian M, Evans AL, Bertelsen MF, Fahlman Å, Haga HA, Ericsson G, and Arnemo JM
- Subjects
- Acepromazine administration & dosage, Adrenergic alpha-2 Receptor Antagonists administration & dosage, Animals, Cross-Sectional Studies, Etorphine administration & dosage, Imidazoles administration & dosage, Muscle Relaxants, Central administration & dosage, Partial Pressure, Sweden, Xylazine administration & dosage, Adrenergic alpha-2 Receptor Antagonists pharmacology, Arteries metabolism, Blood drug effects, Deer, Imidazoles pharmacology, Immobilization veterinary, Oxygen metabolism
- Abstract
Background: The effect of intranasal oxygen and/or early reversal of xylazine with atipamezole on arterial oxygenation in free-ranging moose (Alces alces) immobilized with etorphine-acepromazine-xylazine with a cross-sectional clinical study on 33 adult moose was evaluated., Results: Before treatment the mean±SD (range) partial pressure of arterial oxygen (PaO2) was 62±17 (26-99) mmHg. Twenty-six animals had a PaO2<80 mmHg. Ten had a PaO2 of 40-60 mmHg and three animals had a PaO2<40 mmHg. Intranasal oxygen and intravenous administration of atipamezole significantly increased the mean PaO2, as did the combination of the two. In contrast, atipamezole administered intramuscularly at the evaluated dose had no significant effect on arterial oxygenation., Conclusions: This study shows that intranasal oxygen effectively improved arterial oxygenation in immobilized moose, and that early intravenous reversal of the sedative component, in this case xylazine, in an opioid-based immobilization drug-protocol significantly improves arterial oxygenation.
- Published
- 2014
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