1. Biological sample donation and informed consent for neurobiobanking: Evidence from a community survey in Ghana and Nigeria.
- Author
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Singh, Arti, Arulogun, Oyedunni, Akinyemi, Joshua, Nichols, Michelle, Calys-Tagoe, Benedict, Ojebuyi, Babatunde, Jenkins, Carolyn, Obiako, Reginald, Akpalu, Albert, Sarfo, Fred, Wahab, Kolawole, Sunday, Adeniyi, Owolabi, Lukman F., Adigun, Muyiwa, Afolami, Ibukun, Olorunsogbon, Olorunyomi, Ogunronbi, Mayowa, Melikam, Ezinne Sylvia, Laryea, Ruth, and Asibey, Shadrack
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COMMUNITIES , *BRAIN death , *BRAIN banks , *ETHNIC groups , *POSTSECONDARY education - Abstract
Introduction: Genomic research and neurobiobanking are expanding globally. Empirical evidence on the level of awareness and willingness to donate/share biological samples towards the expansion of neurobiobanking in sub-Saharan Africa is lacking. Aims: To ascertain the awareness, perspectives and predictors regarding biological sample donation, sharing and informed consent preferences among community members in Ghana and Nigeria. Methods: A questionnaire cross-sectional survey was conducted among randomly selected community members from seven communities in Ghana and Nigeria. Results: Of the 1015 respondents with mean age 39.3 years (SD 19.5), about a third had heard of blood donation (37.2%, M: 42.4%, F: 32.0%, p = 0.001) and a quarter were aware of blood sample storage for research (24.5%; M: 29.7%, F: 19.4%, p = 0.151). Two out of ten were willing to donate brain after death (18.8%, M: 22.6%, F: 15.0%, p<0.001). Main reasons for unwillingness to donate brain were; to go back to God complete (46.6%) and lack of knowledge related to brain donation (32.7%). Only a third of the participants were aware of informed consent (31.7%; M: 35.9%, F: 27.5%, p<0.001). Predictors of positive attitude towards biobanking and informed consent were being married, tertiary level education, student status, and belonging to select ethnic groups. Conclusion: There is a greater need for research attention in the area of brain banking and informed consent. Improved context-sensitive public education on neurobiobanking and informed consent, in line with the sociocultural diversities, is recommended within the African sub region. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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