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Background: Recently, a new test (Cuetos-Vega) was developed to detect patients with early symptoms of Alzheimer's disease (AD). This test is rapid, simple and could diagnose patients at early phases of cognitive disorders. The aim of our follow-up study is to evaluate the sensitivity, specificity and predictive values of this test in primary health care (PHC) facilities., Methods: We obtained from our database of La Rambla (village with +/- 8,000 habitants at South Cordoba Health District) the list of asymptomatic independent patients between 66 and 75 years old. A pilot study was conducted with 20 users of La Rambla PHC Centre. This test was modified and adapted for application to our study population. All participants were selected randomly and assigned a date by telephone for the nursing outpatient clinic where the nurse proceeded to administer the screening test. All participants were invited to repeat the same test, together with Pfeiffer test (a short mental status questionnaire), 32 months after the pilot study., Results: The average age of participants was 71.5 ± 2.9 years and 10 (50%) were men. The sensitivity of the new test after 32 months was 50% and the specificity 90.9%. The test had a positive predictive value of 75% and a negative predictive value of 76.9%. The overall accuracy of the test was 76.4%., Conclusion: We present a new test designed to detect patients with mild cognitive impairment and/or early symptoms of AD. A larger cohort is needed to improve the internal validity.

In June 2009, WHO declared the maximum phase alert against H1N1 pandemic flu. Health care workers (HCWs) are considered a strategic target for prevention of the occurrence of H1N1 influenza since they had the greatest risk of acquiring infection. The objectives of our study were (1) identifying the uptake of influenza A(H1N1) 2009 monovalent vaccine by primary health care workers in the southern part of Cordoba, and (2) reporting of the adverse events occurred after vaccination. We followed 240 HCWs in 12 primary health care centres at southern part of Cordoba for vaccine uptake and the occurrence of adverse events. The coverage rate with H1N1 vaccine was 20.5% which was lower compared to seasonal influenza vaccination rate 44.2% in 2009. Males had higher H1N1 vaccination rate compared to females with no significant difference. Senior HCWs complied more with seasonal influenza vaccine while this finding was not consistent with H1N1 vaccination. Multivariate analysis showed that the only independent variable that affected H1N1 vaccine was the compliance to the seasonal flu vaccine in the past three years with OR 5.1 and 95% CI (2.4-10.8). Adverse events occurred among 26.5% of those who complied with H1N1 vaccination. Those were local pain, irritation and induration at site of injection (38.5%), fever (15.4%), fever cough and rhinorrhea (15.4%) generalized pain and lumber pains (23.1%). The low vaccination rate in this study is consistent with previous studies done in many parts of the world and in Spain. Further studies should be done to explore the factors that hindered the uptake and resistance of HCWs to vaccination to H1N1 vaccine., (Copyright © 2011 Elsevier Ltd. All rights reserved.)