1. Effects of COVID-19 Home Confinement on Mental Health in Individuals with Increased Risk of Alzheimer's Disease.
- Author
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Soldevila-Domenech N, Forcano L, Boronat A, Lorenzo T, Piera I, Puig-Pijoan A, Mateus J, González de Echevarri Gómez JM, Knezevic I, Soteras A, Fauria K, Pizarro N, Molinuevo JL, and de la Torre R
- Subjects
- Aged, Aged, 80 and over, Alzheimer Disease diagnosis, Alzheimer Disease genetics, Anxiety Disorders diagnosis, Anxiety Disorders genetics, Anxiety Disorders psychology, Apolipoprotein E3 genetics, Apolipoprotein E4 genetics, COVID-19 genetics, COVID-19 therapy, Cognition Disorders diagnosis, Cognition Disorders genetics, Cognitive Dysfunction diagnosis, Cognitive Dysfunction genetics, Cognitive Dysfunction psychology, Depressive Disorder diagnosis, Depressive Disorder genetics, Depressive Disorder psychology, Female, Humans, Male, Middle Aged, Psychological Distress, Risk, Spain, Alzheimer Disease psychology, COVID-19 psychology, Cognition Disorders psychology, Mental Health, Quarantine psychology
- Abstract
We explored the impact of the Spanish COVID-19 strict home confinement on mental health and cognition in non-infected subjects (N = 16, 60-80 years) diagnosed with subjective cognitive decline and APOEɛ3/ɛ4 carriers. Mental health was monitored for 2 months on a daily, weekly, or monthly basis, and compared to pre-confinement values. Emotional distress, anxiety, and depression scores increased to pathological threshold values during and after confinement. Those with lower mood during confinement experienced a decline in their mood after confinement. Cognition did not change. These preliminary results suggest that mental health consequences of corona measures in preclinical stages of Alzheimer's disease should be further evaluated.
- Published
- 2021
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