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Copyright of Justicia (0124-7441) is the property of Universidad Simon Bolivar and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This work presents a classification of the manufacturing strategies of large Spanish industrial companies in Spain. For this purpose the various international empirical studies on alternative manufacturing strategies have been taken as a reference, reviewed and compared. The database used in this study is made up of information on 114 factories and has been designed using the information from a survey mailed to the industrial companies which have production plants in Spain and which in the financial year of 1994 (reference date of this research) employed over 200 workers. Cluster analysis methodology has been used and the classification criterion taken was the competitive advantages or strengths of each factory concerning the five competitive priorities in manufacturing: efficiency, flexibility, quality, delivery and customer service. Finally, this work identifies a taxonomy of the manufacturing strategies of a sample of the largest industrial companies in Spain, differentiating three alternative production strategies: flexible marketoriented manufacturers, low-cost quality manufacturers and delivery-based manufacturers. Large industrial companies analysed compete in manufacturing, basically following a choice of three criteria: flexibility, quality or delivery. The companies belonging to each of the three categories identified maintain common and lasting manufacturing objectives and policies. [ABSTRACT FROM AUTHOR]

Background: Acetaminophen is extensively used during pregnancy. But there is a lack of population-representative cohort studies evaluating its effects on a range of neuropsychological and behavioural endpoints. We aimed to assess whether prenatal exposure to acetaminophen is adversely associated with neurodevelopmental outcomes at 1 and 5 years of age.Methods: This Spanish birth cohort study included 2644 mother-child pairs recruited during pregnancy. The proportion of liveborn participants evaluated at 1 and 5 years was 88.8% and 79.9%, respectively. Use of acetaminophen was evaluated prospectively in two structured interviews. Ever/never use and frequency of use (never, sporadic, persistent) were measured. Main neurodevelopment outcomes were assessed using Childhood Autism Spectrum Test (CAST), Conner's Kiddie Continuous Performance Test (K-CPT) and ADHD-DSM-IV form list. Regression models were adjusted for social determinants and co-morbidities.Results: Over 40% of mothers reported using acetaminophen. Ever-exposed offspring had higher risks of presenting more hyperactivity/impulsivity symptoms [incidence rate ratio (IRR) = 1.41, 95% confidence interval (CI) 1.01-1.98), K-CPT commission errors (IRR = 1.10, 1.03-1.17), and lower detectability scores (coefficient β = -0.75, -0.13--0.02). CAST scores were increased in ever-exposed males (β = 0.63, 0.09-1.18). Increased effect sizes of risks by frequency of use were observed for hyperactivity/impulsivity symptoms (IRR = 2.01, 0.95-4.24) in all children, K-CPT commission errors (IRR = 1.32, 1.05-1.66) and detectability (β = -0.18, -0.36-0.00) in females, and CAST scores in males (β = 1.91, 0.44-3.38).Conclusions: Prenatal acetaminophen exposure was associated with a greater number of autism spectrum symptoms in males and showed adverse effects on attention-related outcomes for both genders. These associations seem to be dependent on the frequency of exposure. [ABSTRACT FROM AUTHOR]

Seafood consumption during pregnancy is thought to be beneficial for child neuropsychological development, but to our knowledge no large cohort studies with high fatty fish consumption have analyzed the association by seafood subtype. We evaluated 1,892 and 1,589 mother-child pairs at the ages of 14 months and 5 years, respectively, in a population-based Spanish birth cohort established during 2004-2008. Bayley and McCarthy scales and the Childhood Asperger Syndrome Test were used to assess neuropsychological development. Results from multivariate linear regression models were adjusted for sociodemographic characteristics and further adjusted for umbilical cord blood mercury or long-chain polyunsaturated fatty acid concentrations. Overall, consumption of seafood above the recommended limit of 340 g/week was associated with 10-g/week increments in neuropsychological scores. By subtype, in addition to lean fish, consumption of large fatty fish showed a positive association; offspring of persons within the highest quantile (>238 g/week) had an adjusted increase of 2.29 points in McCarthy general cognitive score (95% confidence interval: 0.42, 4.16). Similar findings were observed for the Childhood Asperger Syndrome Test. Beta coefficients diminished 15%-30% after adjustment for mercury or long-chain polyunsaturated fatty acid concentrations. Consumption of large fatty fish during pregnancy presents moderate child neuropsychological benefits, including improvements in cognitive functioning and some protection from autism-spectrum traits. [ABSTRACT FROM AUTHOR]

Copyright of Anuario Turismo y Sociedad is the property of Universidad Externado de Colombia, Facultad de Empresas Turísticas y Hoteleras and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Postprandial TAG-rich lipoproteins (TRL) can be taken up by macrophages, leading to the formation of foam cells, probably via receptor-mediated pathways. The present study was conducted to investigate whether the postprandial time point at which TRL are collected modulates this process. A meal containing refined olive oil was given to nine healthy young men and TRL were isolated from their serum at 2, 4 and 6 h postprandially. The lipid class and apoB compositions of TRL were determined by HPLC and SDS–PAGE, respectively. The accumulation of lipids in macrophages was determined after the incubation of THP-1 macrophages with TRL. The gene expression of candidate receptors was measured by real-time PCR. The highest concentrations of TAG, apoB48 and apoB100 in TRL were observed at 2 h after the consumption of the test meal. However, excessive intracellular TAG accumulation in THP-1 macrophages was observed in response to incubation with TRL isolated at 4 h, when their particle size (estimated as the TAG:apoB ratio) was intermediate. The abundance of mRNA transcripts in macrophages in response to incubation with TRL was down-regulated for LDL receptor (LDLR), slightly up-regulated for VLDL receptor and remained unaltered for LDLR-related protein, but no effect of the postprandial time point was observed. In contrast, the mRNA expression of scavenger receptors SRB1, SRA2 and CD36 was higher when cells were incubated with TRL isolated at 4 h after the consumption of the test meal. In conclusion, TRL led to excessive intracellular TAG accumulation in THP-1 macrophages, which was greater when cells were incubated with intermediate-sized postprandial TRL isolated at 4 h and was associated with a significant increase in the mRNA expression of scavenger receptors. [ABSTRACT FROM PUBLISHER]

This research identifies Action Research as a methodology that can play an important role in enhancing the contribution of universities to the improvement of business competitiveness through Operations Management research. We propose that a Business Chair, defined as an agreement between a university and a business organization, can be a useful tool in research projects based on Action Research methodology. We analyze a set of Business Chairs in the field of Operations Management in Spanish universities. We draw up a set of research questions aiming to determine the degree to which Action Research methodology is used in the Chairs analyzed, and to define the key factors for the successful implementation of Action Research projects. [ABSTRACT FROM AUTHOR]

We present the characterization, by means of three complementary experimental techniques (optical microscopy [OM], scanning electron microscopy equipped with energy dispersive X-Ray spectroscopy [SEM-EDX], and micro-Raman spectroscopy [µRaman]), of a card belonging to a deck of the Spanish pattern made in Perú at the time of Virreinato de Perú (18th century). The objective is to obtain detailed information on the pictorial palette used for the decoration of the cards, where two basic colors, red and green, are seen. Small samples from both colored regions were analyzed. [ABSTRACT FROM AUTHOR]

Purpose--Despite the fact that agile manufacturing has been frequently promoted as a means of improving business competitiveness, little empirical evidence exists in the literature validating its positive link with business performance. The purpose of this research paper is to analyse agile manufacturing in Spain and study whether it is a critical factor for success in different industries. Design/methodology/approach--A conceptual model is drawn up, based on the literature and a previous case study, to relate turbulence in the environment with agile manufacturing practices and business performance. The model is tested on a large sample of Spanish manufacturers using a survey methodology to obtain information and a structural equation model to analyse the data. Findings--The results obtained show that, in turbulent environments, the integrated use of agile manufacturing practices promotes manufacturing competitive strength, leading to better operational, market and financial performance. Research limitations/implications--This study has two main limitations. First, it is difficult to determine the most suitable unit of analysis when studying agile manufacturing. Second, single respondent bias may be considered a limitation. Practical implications--Managers should consider the integrated implementation of agile manufacturing practices in order to develop manufacturing strength and to outperform competitors in turbulent business environments. Originality/value--This study adopts a systematic approach to the analysis of agile manufacturing, considering various agility practices or enablers in an integrated way and relating them not only to environmental characteristics but also to business performance. This approach is especially interesting because most of the literature on agile manufacturing deals with agility strategies or techniques in an isolated way. The study also tests the suitability of agile manufacturing in real organizations--for the first time in the... [ABSTRACT FROM AUTHOR]

The aim of this work is to analyse the manufacturing strategies of the large Spanish industrial companies during the 1990s, making a comparison with the experience of American and other European manufacturers. To this end, and taking 1994 as a reference, this paper describes the planning process and content of the of the manufacturing strategies of a representative sample of the largest industrial companies in Spain, analysing, in particular, the high priority manufacturing objectives and policies maintained during the period 1992-1993 and those foreseen for the period 1995-1999. The information analysed has been obtained from a mail survey. The comparison of the Spanish companies with American and other European manufacturers attempts to observe how the Spanish experience is similar to that of other countries, in order to obtain interesting conclusions for the managers who may be responsible for managing industrial companies located in Spain. [ABSTRACT FROM AUTHOR]