1. Acute hepatitis due to hepatitis A virus during the 2017 epidemic expansion in Asturias. Spain.
- Author
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Fraile M, Barreiro Alonso E, de la Vega J, Rodríguez M, García-López R, and Rodríguez M
- Subjects
- Acute Disease, Adult, Alanine Transaminase blood, Comorbidity, Female, HIV Infections epidemiology, Hepatic Encephalopathy etiology, Hepatitis A blood, Hepatitis A complications, Hepatitis A transmission, Humans, Liver Failure etiology, Male, Middle Aged, Prospective Studies, Prothrombin Time, Sexual Behavior, Sexual and Gender Minorities statistics & numerical data, Spain epidemiology, Syphilis epidemiology, Disease Outbreaks, Hepatitis A epidemiology
- Abstract
Introduction: Since June 2016, there has been an increase in cases of acute hepatitis A (AHA) in several European countries, mainly affecting men who have sex with men (MSM). The aim was to know the characteristics of AHA diagnosed in recent months, comparing them with a previous series., Patients and Methods: All cases of AHA diagnosed in adults between November 2016 and December 2017 (G-I; n=108) were prospectively collected and compared with a series also prospectively collected between January 2004 and September 2016 (G-II; n=49), analysing clinical and epidemiological characteristics., Results: Compared with group II, in group I there was a greater proportion of males (95.4 vs. 81.6%; p=0.005), of MSM (63.9 vs. 22.4%; p<0.001), of cases with positive luetic serology (20.4 vs 2%; p=0.001) and of severe acute hepatitis (15 vs. 4%; p=0.043)., Conclusions: AHA diagnosed in recent months in our environment mainly affect MSM and have a more serious presentation with respect to what was observed in a historical series, highlighting the need to increase the vaccination rate against the hepatitis A virus., (Copyright © 2018 Elsevier España, S.L.U. All rights reserved.)
- Published
- 2019
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