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Treatments for breast cancer often include interventions related to psychosocial issues such as negative body image, loss of femininity, and low self-esteem. We identified the psychological effects of a cosmetics education programme in patients with breast cancer. Cosmetic programme is a specific care designed to help patients handle appearance-related side effects. Thirty-one women with breast cancer at a university hospital in South Korea who received a cosmetics education programme were compared with 29 subjects in a control group who received the treatment as usual. Psychological factors including distress, self-esteem, and sexual functioning were assessed three times (before and after the programme, and at the 1-month follow-up). After the programme, patients in the treatment group were significantly less likely than those in the control group to rely on distress ( P = 0.038) and avoidance coping ( P < 0.001) but not on self-esteem. The mean scores in the treatment group for sexual functioning were higher than those in the control group after the treatment. Our results suggest the potential usefulness of a brief cosmetics education programme for reducing distress and reliance on negative coping strategies. Implementing a cosmetics programme for patients with breast cancer may encourage patients to control negative psychological factors. [ABSTRACT FROM AUTHOR]

The article discusses a study that compares the efficiency of two hydrocolloid dressings that is used for the management of lacerations, abrasions, and minor operation incisions in acute trauma wounds in South Korea. The two dressing which were compared are Medifoam H (MH) or DuoDERM (DD). It concludes that no difference was found between Medifoam H and DuoDERM dressing for minor, acute trauma wound management.

This study aims to validate a model for evaluating learning management systems (LMS) used in e-learning fields. A survey of 163 e-learning experts, regarding 81 validation items developed through literature review, was used to ascertain the importance of the criteria. A concise list of explanatory constructs, including two principle factors, was extracted from the responses of 133 respondents by exploratory factor analysis. Factor I was labeled as ‘instruction management, screen design, and technology’ and factor II, ‘interaction and evaluation’. Factors I and II consisted of four and three sub-factors, respectively. Confirmatory factor analysis, in turn, was carried out to assess the degree to which the plausibility of factor models was empirically confirmed. Overall fit measures (RMSEA, CFI, NNFI indexes) showed the model to be quite suitable for LMS evaluation. Reliability estimates using Cronbach's alpha indicated that the evaluation tool had good internal consistency. The overall results of the analyses suggest that this evaluation tool is highly instrumental for LMS. [ABSTRACT FROM AUTHOR]

Abstract Background This 24-week, multicenter, randomized, exploratory, comparative, open-label, phase-IV study assessed the safety and efficacy of prolonged-release tacrolimus (PR-T) with reduced-dose versus standard-dose corticosteroids in stable kidney transplant recipients in Korea after converting from cyclosporine-based therapy. Methods At baseline, patients were converted from cyclosporine-based to PR-T-based immunosuppression and randomized (1:1) to receive either corticosteroids maintained at prestudy dose (standard-dose group) or tapered from week 4 to 50% of the prestudy dose by week 12 (reduced-dose group). Patients were seen at baseline and weeks 1, 4, 12, and 24. The primary endpoint was change in estimated glomerular filtration rate (Modification-of-Diet-in-Renal-Disease-4) between baseline and week 24. Secondary endpoints included either acute rejection or patient-reported satisfaction with PR-T. Adverse events (AEs) were recorded. Results Overall, 150 patients were randomized into a reduced-dose group (n = 73) and a standard-dose group (n = 77). At week 24, mean ± standard deviation for corticosteroid dose was 2.5 ± 0.9 mg and 5.0 ± 1.3 mg, respectively. Mean change in estimated glomerular filtration rate from baseline to week 24 was +1.5 ± 9.1 mL/min/1.73 m2 (P =.1567) and +3.4 ± 10.6 mL/min/1.73 m2 (P =.0065), respectively, and not significantly different between groups. There were no acute rejection episodes. Most respondents (>70%) considered PR-T more convenient than cyclosporine. AE incidence was similar between groups. The most common AEs experienced by ≥3% of patients in either treatment group were gastrointestinal events (20.8% and 28.6% of patients receiving reduced- and standard-dose corticosteroids, respectively). Most AEs in both treatment groups were mild or moderate in severity. Conclusion Renal function was maintained following conversion from cyclosporine to PR-T, irrespective of corticosteroid regimen; PR-T enables reduced corticosteroid dosage. Highlights • Prolonged-release tacrolimus dose was similar in the reduced- vs standard-dose group post conversion from cyclosporine. • Similar, stable prolonged-release tacrolimus trough blood levels were observed between treatment groups. • No significant difference in estimated glomerular filtration rate was seen between treatment groups at baseline and week 24. • Most patients (>70%) considered prolonged-release tacrolimus more convenient than cyclosporine. • Most adverse events in both treatment groups were mild or moderate in severity. [ABSTRACT FROM AUTHOR]