1. Silent dissemination of colistin-resistant Escherichia coli in South America could contribute to the global spread of the mcr-1 gene.
- Author
-
Fernandes MR, Moura Q, Sartori L, Silva KC, Cunha MP, Esposito F, Lopes R, Otutumi LK, Gonçalves DD, Dropa M, Matté MH, Monte DF, Landgraf M, Francisco GR, Bueno MF, de Oliveira Garcia D, Knöbl T, Moreno AM, and Lincopan N
- Subjects
- Animal Feed microbiology, Animals, Anti-Bacterial Agents therapeutic use, Asymptomatic Infections epidemiology, Drug Resistance, Bacterial, Escherichia coli classification, Escherichia coli Infections epidemiology, Escherichia coli Infections veterinary, Food Contamination analysis, Food Microbiology statistics & numerical data, Global Health statistics & numerical data, Humans, South America epidemiology, Animals, Domestic microbiology, Colistin therapeutic use, Escherichia coli drug effects, Escherichia coli isolation & purification, Escherichia coli Infections microbiology, Escherichia coli Proteins metabolism
- Abstract
During a Brazilian multicentric antimicrobial resistance surveillance study, colistin resistance was investigated in 4,620 Enterobacteriaceae isolated from human, animal, food and environmental samples collected from 2000 to 2016. We present evidence that mcr-1-positive Escherichia coli has been emerging in South America since at least 2012, supporting a previous report on the possible acquisition of mcr-1-harbouring E. coli by European travellers visiting Latin American countries.
- Published
- 2016
- Full Text
- View/download PDF