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Background: Neglected tropical diseases (NTDs) primarily affect the poorest populations, often living in remote, rural areas, urban slums or conflict zones. Arboviruses are a significant NTD category spread by mosquitoes. Dengue, Chikungunya, and Zika are three arboviruses that affect a large proportion of the population in Latin and South America. The clinical diagnosis of these arboviral diseases is a difficult task due to the concurrent circulation of several arboviruses which present similar symptoms, inaccurate serologic tests resulting from cross-reaction and co-infection with other arboviruses. Objective: The goal of this paper is to present evidence on the state of the art of studies investigating the automatic classification of arboviral diseases to support clinical diagnosis based on Machine Learning (ML) and Deep Learning (DL) models. Method: We carried out a Systematic Literature Review (SLR) in which Google Scholar was searched to identify key papers on the topic. From an initial 963 records (956 from string-based search and seven from a single backward snowballing procedure), only 15 relevant papers were identified. Results: Results show that current research is focused on the binary classification of Dengue, primarily using tree-based ML algorithms. Only one paper was identified using DL. Five papers presented solutions for multi-class problems, covering Dengue (and its variants) and Chikungunya. No papers were identified that investigated models to differentiate between Dengue, Chikungunya, and Zika. Conclusions: The use of an efficient clinical decision support system for arboviral diseases can improve the quality of the entire clinical process, thus increasing the accuracy of the diagnosis and the associated treatment. It should help physicians in their decision-making process and, consequently, improve the use of resources and the patient's quality of life. Author summary: Neglected tropical diseases (NTDs) primarily affect the poorest populations, often living in remote, rural areas, urban slums or conflict zones. Arboviruses are a significant NTD category spread by mosquitoes. Dengue, Chikungunya, and Zika are three arboviruses that affect a large proportion of the population in Latin and South America. The clinical diagnosis of these arboviral diseases is a difficult task due to the concurrent circulation of several arboviruses which present similar symptoms and, sometimes, inaccurate test results. In this paper, we present the state of the art of studies investigating the automatic classification of arboviral diseases based on Machine Learning (ML) and Deep Learning (DL) models. Results show that current research is focused on the classification of Dengue, primarily using tree-based ML algorithms. The use of an efficient clinical decision support system for arboviral diseases can improve the quality of the entire clinical process, thus increasing the accuracy of the diagnosis and the associated treatment. It should help physicians in their decision-making process and, consequently, improve the use of resources and the patient's quality of life. [ABSTRACT FROM AUTHOR]

Social distancing is a powerful non-pharmaceutical intervention used as a way to slow the spread of the SARS-CoV-2 virus around the world since the end of 2019 in China. Taking that into account, this work aimed to identify variations on population mobility in South America during the pandemic (15 February to 27 October 2020). We used a data-driven approach to create a community mobility index from the Google Covid-19 Community Mobility and relate it to the Covid stringency index from Oxford Covid-19 Government Response Tracker (OxCGRT). Two hypotheses were established: countries which have adopted stricter social distancing measures have also a lower level of circulation (H1), and mobility is occurring randomly in space (H2). Considering a transient period, a low capacity of governments to respond to the pandemic with more stringent measures of social distancing was observed at the beginning of the crisis. In turn, considering a steady-state period, the results showed an inverse relationship between the Covid stringency index and the community mobility index for at least three countries (H1 rejected). Regarding the spatial analysis, global and local Moran indices revealed regional mobility patterns for Argentina, Brazil, and Chile (H1 rejected). In Brazil, the absence of coordinated policies between the federal government and states regarding social distancing may have played an important role for several and extensive clusters formation. On the other hand, the results for Argentina and Chile could be signals for the difficulties of governments in keeping their population under control, and for long periods, even under stricter decrees. [ABSTRACT FROM AUTHOR]