1. Screening for acrylate/methacrylate allergy in the baseline series: our experience in Sweden and Singapore.
- Author
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Goon AT, Bruze M, Zimerson E, Goh CL, Soo-Quee Koh D, and Isaksson M
- Subjects
- Acrylates adverse effects, Adolescent, Adult, Age Distribution, Aged, Aged, 80 and over, Allergens chemistry, Child, Dermatitis, Allergic Contact diagnosis, Dermatitis, Allergic Contact epidemiology, Female, Hand Dermatoses chemically induced, Hand Dermatoses epidemiology, Humans, Incidence, Male, Methacrylates chemistry, Middle Aged, Patch Tests methods, Sex Distribution, Singapore epidemiology, Sweden epidemiology, Young Adult, Acrylates immunology, Dermatitis, Allergic Contact etiology, Mass Screening methods, Methacrylates adverse effects
- Abstract
Background: No studies to specifically determine the prevalence of contact allergy to acrylates/methacrylates in patch tested populations have been published., Objectives: To determine the prevalence of acrylate/methacrylate allergy in all patients tested to the baseline patch test series., Methods: Five acrylate/methacrylate allergens (2-hydroxyethyl methacrylate, methyl methacrylate, ethylene glycol dimethacrylate, triethylene glycol diacrylate, and 2-hydroxypropyl acrylate) were included in the baseline series for at least 2 years in Malmö and Singapore., Results: Thirty-eight patients in total had reacted to acrylate/methacrylate allergens in the baseline series during the study period in both populations. In Malmö, there were 26 (1.4%) patients with positive patch tests to acrylate/methacrylate allergens, 14 of whom had relevant reactions. In Singapore, there were 12 (1.0%) patients with positive patch tests to acrylate/methacrylate allergens, but only 1 had relevant reactions. If we had not added acrylate/methacrylate allergens to the baseline series, we would not have patch tested 13/26 (50%) of the positive reactors in Malmö and 11/12 (92%) of the positive reactors in Singapore. The overall proportion of missed positive reactors would have been 24/38 (63%)., Conclusions: The prevalence of acrylate/methacrylate allergy in our patch tested dermatitis populations is 1.4% in Malmö and 1.0% in Singapore.
- Published
- 2008
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