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Disease prevention and control are a crucial aspect of fishery management, as they ensure the sustainability of aquacultural systems. With a specific focus on Shandong Province, China, this study outlines the occurrence of diseases in aquatic organisms. It summarizes dynamics that drive disease prevention and control and supports technology, work mode, and emergency prevention and control. In addition, this study also delves into the role of epidemic prevention and control institutions, the upgrading of the social service of disease prevention systems, and insufficient technical support for new species and models. Overall, the findings outlined in this study are intended to achieve the following aims: enhance organizational management of disease prevention and control, standardize the implementation of social services, improve research into prevention and control technologies, and highlight the importance of information technology in disease prevention and control. Based on practical aquaculture production, our aim is to comprehensively analyze the situation of the construction of a disease prevention and control system, strengthen guidance on epidemic prevention technologies, establish a robust animal epidemic prevention system, and propose development strategies, serving as a reference for competent authorities to enhance the disease prevention and control of aquatic organisms. [ABSTRACT FROM AUTHOR]