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Number one of the health problems now is stress. It is regarded as the biggest problem in many countries around the world, especially for both employees and organizations. As a result of the work demands, job stress arises among employees and organizations. It is a complex phenomenon. That is caused by many factors. Job stress plays a main role in the resulting performance of the individuals within any kind of organization they serve for. It is regarded as a harmful factor for employees in terms of health and job dissatisfaction, as well as for organizations in terms of productivity. Therefore, job stress hurts different kinds of occupations. As well as, it has different types which are caused by the nature and the demands of the job. This study aimed to investigate the relationship between the effect of job stress on job satisfaction for nurses working in a psychiatric hospital. Methodology: A descriptive study was conducted among nursing staff in psychological hospitals in the Kingdom of Saudi psychiatric hospitals. The process of the necessary data collection began from 20th May - 30th July 2021 and was obtained through a self-report convenient sample of (115) nursing, nursing directors, and heads of nursing departments located in the Kingdom of Saudi psychiatric hospitals by using a questionnaire divided into three parts: First, socio-demographic characteristics consisted of eight items. Second, Expanded Nursing Stress Scale (ENSS) is built from (57) items ranging in nine sub-scales. Third, the Job Satisfaction Survey (JSS), included 36 items in nine subscales. validity of the questionnaire was decided through a panel of (11) experts in different fields and work settings. Conclusions: Approximately (1/4) of participating nurses haven't a profession that fits with interest. Nurses had satisfied with their work. No bickering and fighting at work. the shortage and delay in payment (salary) are major causes of increasing job stress and decreasing job satisfaction, although the extent of job stress among nurses is not recorded high and most of them are satisfied with their job. there have been a good relationship and effective communication among nurse's staff. [ABSTRACT FROM AUTHOR]

Background: Hyperekplexia is a rare disorder characterized by exaggerated startle responses to unexpected sensory stimuli, recurrent apneas, and stiffness. Only few studies have been published on this disorder in populations with high rates of consanguinity.Methods: We retrospectively reviewed Saudi patients with genetically confirmed hereditary hyperekplexia using a standard questionnaire that was sent to nine major referral hospitals in Saudi Arabia.Results: A total of 22 Saudi patients (11 males, 11 females) from 20 unrelated families who had hereditary hyperekplexia were included. Based on molecular studies, they were classified into different subtypes: SLC6A5 variant (12 patients, 54.5%), GLRB variant (seven patients, 31.8%), and GLRA1 variant (three patients, 13.7%). All patients were homozygous for the respective causal variant. The combined carrier frequency of hereditary hyperekplexia for the encountered founder mutations in the Saudi population is 10.9 per 10,000, which translates to a minimum disease burden of 13 patients per 1,000,000.Conclusion: Our study provides comprehensive epidemiologic information, prevalence figures, and clinical characteristics of a large cohort of patients with hereditary hyperekplexia. [ABSTRACT FROM AUTHOR]