1. Disseminated intestinal basidiobolomycosis with mycotic aneurysm mimicking obstructing colon cancer.
- Author
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Omar Takrouni A, Heitham Schammut M, Al-Otaibi M, Al-Mulla M, and Privitera A
- Subjects
- Adolescent, Aneurysm, Infected diagnostic imaging, Aneurysm, Infected microbiology, Diagnosis, Differential, Fatal Outcome, Female, Gastrointestinal Tract diagnostic imaging, Gastrointestinal Tract microbiology, Humans, Intestinal Obstruction diagnostic imaging, Intestinal Perforation diagnosis, Intestines, Saudi Arabia, Sepsis complications, Sepsis diagnosis, Tomography, X-Ray Computed methods, Zygomycosis diagnosis, Aneurysm, Infected complications, Colonic Neoplasms, Entomophthorales isolation & purification, Intestinal Obstruction complications, Intestinal Perforation complications, Zygomycosis complications
- Abstract
Basidiobolomycosis is a rare fungal infection that may affect the gastrointestinal tract. It is caused by Basidiobolus ranarum and less than 80 cases have been reported in the literature. The incidence seems to be higher in the Middle East and in particular Saudi Arabia where most cases are diagnosed in the south-western region. An 18-year-old woman presented to the emergency department with an obstructing caecal mass initially suspected to be malignant. Surgical resection was complicated by bowel perforation, histology and cultures confirmed basidiobolomycosis infection. The postoperative course was complicated by an enterocutaneous fistula, fungal intra-abdominal abscesses, liver and lung abscesses, formation of mycotic hepatic artery aneurysm and meningoencephalitis. The patient eventually expired due to sepsis despite aggressive treatment. Diagnosis and management of such rare cases are very challenging and require a multidisciplinary approach. Complications are common and associated with a high mortality., Competing Interests: Competing interests: None declared., (© BMJ Publishing Group Limited 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
- Published
- 2019
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