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As sustainable urban communities continue to seek alternative energy sources, this study explores the inclusion of renewable resources in the energy mix. With a focus on liquefied natural gas (LNG) regasification, parabolic trough solar collectors, dual-loop power cycles, proton exchange membrane electrolysis, and hydrogen liquefaction cycle, this research conducts a comprehensive examination of an integrated system. The primary objective is to provide a diverse range of valuable outputs, including electricity, liquefied hydrogen, desalinated water, and cooling for coastal areas. Through careful analysis of regional geographic features, San Francisco emerges as a suitable location due to its favorable solar radiation intensity and existing LNG transportation infrastructure. The findings reveal that the integrated system has the potential to deliver approximately 5750.4 MWh of cooling, 14988.85 MWh of electricity, and 1,491,084 m3 of fresh water, thereby significantly contributing to the city's utility demands. In terms of data-driven optimization, artificial neural networks serve as intermediary mechanisms to establish correlations between the developed code and the optimization algorithm. The results demonstrate that the optimized system exhibits notable improvements in production capacity. Moreover, significant reductions in the levelized cost of electricity (0.19 Cent/kWh), fresh water (1.22 Cent/m3), and hydrogen (0.08 $/kg) are observed. Although the optimized case entails a 16.11% higher cost rate compared to the base system, it is projected to generate a 25.59% higher profit over its operational lifespan. Additionally, the payback period of the optimized system is shortened by 6.31%, making it an attractive long-term investment for sustainable urban development. [Display omitted] • Designing a solar and LNG-based multigeneration system for coastal areas. • Incorporating a hydrogen liquefaction unit for efficient storage of hydrogen. • Applying dynamic techno-economic and environmental appraisals to analyze the system. • Performing multi-criteria and machine learning approaches to optimize the system. • The payback period of the optimized system has been shortened by 5.31%. [ABSTRACT FROM AUTHOR]