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One of the poorly studied and widespread plants in the Russian Far East is the Manchurian saw-wort (Serratula manshurica Kitag.). It is known that this plant is rich in phytoecdysteroids, which have high biological activity (anabolic, adaptogenic, cardiotropic, immunomodulatory effects). Two biologically active compounds of the flavonoid class were isolated from the aerial part of Serratula manshurica Kitag., growing in the Primorskii krai of the Far East of Russia by liquid extraction and recrystallization methods: quercetin-4'-O-β-D-glucuronopyranoside and apigenin-7-O-β-D-glucuronopyranoside. The structure of the isolated compounds was demonstrated by UV, NMR spectroscopy and mass spectrometry with electrospray ionization. The quantitative content of flavonoids in the aerial part of the Serratula manshurica plant in different phenological phases of plant development (luteolin-4'-O-β-D-glucuronopyranoside, quercetin-4'-O-β-D-glucuronopyranoside, apigenin-7-O-β-D-glucuronopyranoside, 3-methylquercetin -4'-O-β-D-glucuronopyranoside, quercetin, apigenin, 3-methylquercetin, luteolin, isokaempferide) was determined by the method of reversed phase liquid chromatography (RP HPLC). It was shown that the maximum content of flavonoid aglycones in plants was observed during the beginning of the growing season and in the budding phase, and their glycosides during the flowering phase. Thus, to obtain plant material with the maximum content of flavonoid aglycones (quercetin, 3-methylquercetin, luteolin) the collection of vegetative mass should be carried out during the beginning of the growing season, and their glycosides during the flowering period. Serratula manshurica Kitag., which grows abundantly on the territory of Primorskii krai, can be considered a constantly renewable and promising source for obtaining flavonoids. [ABSTRACT FROM AUTHOR]

The article presents results of a thermographic examination of the hands of young people belonging to different geographical populations, the indigenous inhabitants of the European North of Russia and South Asia. To identify the features of temperature reactions of the contralateral (left) hand with local cooling of the right in young people who are not adapted to the cold climate, migrants from South Asia (India) was conducted. Thermal photographs of the hands were taken by the method of infrared thermography by means of a thermal imaging camera (NEC-900, Japan). In total, 48 people took part in the survey, among them 24 people (11 women and 13 men) were natives of South Asia (SA group) and 24 people (12 women and 12 men) permanently resided in the territory of the European North of Russia (ENR group). As a result of the study, significant differences between the SA and ENR in nominal values of the background temperature of the skin surface of the contralateral hand, as well as the temperature of the hand at each stage of the recovery period after a local cold test were found. In comparison with the ENR group a significantly lower value of the brush temperature in the SA group was revealed. At the same time, a similar dynamics of temperature changes of the contralateral hand manifested in a gradual increase in the temperature of the contralateral hand after a cold test was common to both groups. [ABSTRACT FROM AUTHOR]

The genus Serratula L. (the Asteraceae family) is represented by two species in the Russia's Far East: Serratula manshurica Kitag. and Serratula komarovii Iljin, which are potential sources of biologically active compounds (phytoecdysteroids). Using liquid extraction with 70% ethanol and reverse-phase high-performance liquid chromatography (RP HPLC), six representatives of the flavonoid class in the above-ground parts (leaves, stems, and inflorescences) of S. komarovii growing in the Primorskii krai of the Far East of Russia, are identified for the first time: luteolin-7-O-β-D-glucuronopyranoside, apigenin-7-O-β-D-glucuronopyranoside, chrysoeriol-7-O-β-D-glucuronopyranoside, quercetin, luteiolin, and 3-methylquercetin. The structure of the compounds luteolin-7-O-β-D-glucuronopyranoside, apigenin-7-O-β-D-glucuronopyranoside, and chrysoeriol-7-O-β-D-glucuronopyranoside, which are isolated by preparative column chromatography on silica gel using gradient elution with a mixture of carbon tetrachloride and ethanol, is established by UV, 1H and 13C NMR, and 1H−13C heteronuclear multiple bond correlation (HMBC) spectroscopies. Luteolin-7-O-β-D-glucuronopyranoside is found to be the major flavonoid in S. komarovii (its content in leaves and stems is 4.92 ± 0.98% and 1.23 ± 0.25%, respectively), and apigenin-7-O-β-D-glucuronopyranoside is the dominant flavonoid found in inflorescences (1.10 ± 0.22%). Total flavonoids in the above-ground organs of S. komarovii are determined by differential spectrophotometry; their content varies from 1.96 to 9.04 wt %. The highest flavonoid content is found in leaves (9.04 ± 0.71%), and the lowest content is found in stems of the plant (1.96 ± 0.20%). As a result, S. komarovii can be a promising and constantly renewable source of not only phytoecdysteroids but also flavonoids for the pharmaceutical industry. [ABSTRACT FROM AUTHOR]

The use of nuclear energy on submarines has made autonomous and independent navigation possible for long periods of time. OKBM Afrikantov – one of the leading enterprises of the Rosatom State Corporation – has been supplying Russia's naval ships with nuclear reactor installations for more than 65 years commencing with the development of equipment for the installations on first-generation submarines. Currently, all active ships – second, third, and fourth generation submarines and nuclear surface ships – are powered by reactor installations developed by OKBM. Commencing with the complete nuclear reactor installation set for the Yasen class nuclear submarine, OKBM has functioned as the complete supplier of equipment for all installations developed and being developed for ships and vessels which are under construction or being modernized. Currently, OKBM is designing ship nuclear reactor installations for promising naval ships. [ABSTRACT FROM AUTHOR]

We consider some theoretical and methodological issues relating to stability assessment of natural development of vegetation in geosystems. We have ascertained the evolutionary-genetic essentials of vegetation stability and presented the cartographic states of its assessment. The stability map for plant communities has been developed on a conjugate scale of predictive-cartographic products. [ABSTRACT FROM AUTHOR]

Electrophysiological and psychophysiological studies were performed in a group of seven- to eight-year-old children, who had been born and lived in Arkhangelsk, with various risk factors of early dysontogeny. Analysis of the data demonstrated that “disturbing” factors affected maturation of the neuronal apparatus of the cerebral cortex. In children from risk groups, the immaturity of cortical rhythmogenesis was expressed in the inconsistency with the functional loads of the main rhythm at rest and of the α rhythm response. Depending on the risk factors of early dysontogeny, the examined children were divided into groups differing in the phenomena of functional immaturity of the cerebral cortex and in psychophysiological functions. An injury at birth to a child and a combination of numerous risk factors of early dysontogeny has the most negative effect on the functional maturity of the rhythmogenic structures of cerebral cortex. [ABSTRACT FROM AUTHOR]

Talks about the impact of the development of technology policy on economic transformation in Russia. Principal aspects of technology policy; Primary functions of technological policy to which it is conditional; Problems of technological policy.

We explored cultural-level variables and their associations with missing data in a group of immigrants from the Former Soviet Union (FSU). Elderly hypertensive women (N = 105) completed a health survey. Prevalence of missing data and z scores were calculated to determine which survey items and measures were more likely to have missing data. Hierarchical linear regressions were performed to test whether cultural variables predicted the rate of missing data beyond individual variables. Culture variables associated with survey nonresponse and missing data were related to depression, anxiety, medication beliefs and practices, attitudes toward physicians, and cultural and behavioral identity. An interpretation of the patterns of missing data and strategies to reduce the likelihood of missing data in this population are discussed. Cultural norms likely influence patients' orientations toward their health care providers. Providers would do well to normalize difficulties with medical adherence and encourage patients to ask questions about such directives. We recommend that researchers consider the cultural appropriateness of survey items and consider alternative methods (i.e., qualitative designs) for culturally sensitive topics such as mental health and sexuality.

The article covers data on occupational risk of occupationally mediated and occupational diseases, according to periodic medical examinations in 53251 workers of industrial enterprises in Arkhangelsk city. The authors justify a system of health risks management.

The authors gave scientific basis for system evaluating occupational risk and managing workers' health disorders, according to periodic medical examinations data, to ambient levels of environmental (including occupational) hazards, exemplified by industrial complex in Arkhangelsk city. This scientific basis helped to define categories and levels of occupational risk, etiologic share of hazards in disease development, index of occupational diseases, cause effect relationships of disease development and work conditions and other environmental factors, to specify management solutions on lowering occupational risk.

The data on leptospirosis morbidity among agricultural animals and humans in the Stavropol Territory for the last 10 years, as well as the serological picture of the causative agent of leptospirosis, are presented. The epidemiological importance of the main risk factors and their influence on the development and manifestations of the epidemic process are substantiated. As revealed in this investigation, the professional character of leptospirosis morbidity among humans has been almost completely lost under modern conditions, which requires further study with a view to the development of the rational complex of prophylactic measures.

Specialist gynecology care practice development in a center of consultation and diagnosis with more than 15,000 women beneficiaries in its books and 26 military clinics for consultation services.

Two outbreaks of virus hepatitis were etiologically and epidemiologically interpreted. In this work the original method of obtaining washings, with their subsequent concentration, from the suspected foodstuff was used and hepatitis A virus was then detected in concentrated washings in the enzyme immunoassay, which made it possible to confirm the contribution of the alimentary factor of the transfer of infection (sun-cured melon) in the above-mentioned outbreaks. The data thus obtained are indicative of the necessity to conduct epidemiological investigation, taking into account the possibility of contacting hepatitis A when using foodstuffs not subjected to preliminary treatment.