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A new study of a historical object on the territory of the Russian Federation, the Holy Trinity Danilov Monastery, implemented by the muon radiography is presented. The method is based on the registration of changes in the cosmic muon fluxes during their passage through the object under study. Nuclear photoemulsions with unique spatial and angular resolution having the widest range of applications in experimental nuclear physics were used as experimental equipment. The experiment demonstrates a high efficiency of the method in the search for hidden objects, the presence of which on the territory of the monastery is confirmed by the results obtained. [ABSTRACT FROM AUTHOR]

Objective of the study were: to specify the features of clinical presentations and dynamics of anorexia nervosa (AN) developed in adolescence during the current depression; to study affective disorders preceding the onset of AN and to analyze comorbidity of these two pathologies. We examined 21 female patients, aged from 15 to 17 years old (mean age 16.7 ± 0.8 years). It was shown that depressive symptoms developed 4-11 months (mean 7.9 ± 2.5 months) before the onset of AN. The development of AN was associated with depression and might be considered as one of mechanisms of formation of eating disorders that might be termed as affective mechanism. Thus, we can specify a variant of adolescent/juvenile depression, or depression with eating disorders. The variant represents a protracted depressive state with overvalued ideas to improve body image and to restrict calories which is combined with adynamic affect associated with anxiety, melancholy and dysphoria.

After introducing surveillance for poliomyelitis and AFP cases in the Russian Federation in 1998, 740 AFP cases have been registered in 1998-1999, and 18 of that number were considered as vaccine-associated paralytic poliomyelitis (VAPP). Of 18 cases 11 were classified as VAPP of vaccine recipients and confirmed by virus isolation; from two of the vaccine recipients virus was not isolated, and five were poliomyelitis cases in contact non-vaccinated children. In all the cases the disease was characterised with the typical clinical picture with residual pareses and paralyses. One case was fatal. Vaccine virus type 3 has been isolated from all the vaccine recipients. The MAPREC test has shown that the quality of monovaccine type 3 bulks used for vaccinating these children did not differ from the quality of other bulk vaccines produced by the Chumakov Institute of Poliomyelitis. Patients surveyed for gammaglobulin were positive. Polioviruses type 1 isolated from two of the contact cases had changed antigenic properties and were recombinants of types 1 and 2.

The word deals with the results obtained in the study of the reactogenicity and immunological activity of concentrated and inactivated tissue-culture tick-borne encephalitis vaccine, manufactured by the Chumakov Institute of Poliomyelitis and Viral Encephalitides, in the immunization of children and adolescents. The vaccine proved to be moderately reactogenic and exhibited pronounced immunological activity. In 91.5% of the immunized children the fourfold increase of the antibody level was observed. On the basis of the data obtained in this study the tick-borne encephalitis vaccine was recommended for use in medical practice for the prophylaxis of tick-borne encephalitis among children and adolescents.

The automated system for mass examination and follow-up of therapeutic patients has been developed, tested and introduced with the help of computer family "Electronics" and "IBM". The system is designed for the use at polyclinics, health units and health centres. The following programmes are provided: premedical screening, ECG data interpretation, analysis of physician's data and management of follow-up, primary and secondary prevention of chronic diseases. The application of this system in 2336 persons resulted in substantial saving of physician's time during mass examinations, improved the quality of screening and follow-up.