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Eisenmenger Syndrome is a rare constellation of symptoms due to untreated congenital heart disease with right to left shunt and increased pulmonary arterial hypertension. A female of 58 years old came to ER with respiratory failure and upon evaluation found to have Eisenmenger syndrome. Intensive work up concluded in medical management with patient. Eisenmenger syndrome patients' need to be closely monitored once diagnosed owing to decreased life expectancy. [ABSTRACT FROM AUTHOR]

Background and Objectives: Presently world is facing Corona virus disease pandemic. This disease was first identified in Wuhan city of China which spread rapidly to more than 200 countries including India. Rajasthan is a state affected badly with this disease. So this present study was conducted to find out the status of COVID-19 in state and to find out the effects of containment measures taken. Materials and Methods: This record base case series type of study was conducted from reports received of confirmed COVID-19 cases and reported to the IDSP, DMHS from March 2nd 2020 to May 25th 2020, from various reporting units of Rajasthan. Desired information's were collected, compiled and analyzed. Interpretation and Conclusion: There were 7351 laboratory-confirmed case including 4061 recovered cases and 166 deaths. Recovery rate and Case Fatality Rate were found 55.24% and 2.26% respectively. (2.4%) reported. Although patients of all ages were affected with this disease but majority (81.99%) were in 16-60 years of age group. In these positive cases male predominance was also observed with M:F ratio 2.11. Majority of district of Rajasthan were affected with this pandemic having about half of cases in three districts v.i.z. in Jaipur, Jodhpur and Udaipur districts. Average Doubling time has increased from 4 days to 18 days as a result of containment measures undertaken in Rajasthan. So these containment measures like social distancing, masking, washing hand frequently etc. Should be taken care of even after lockdown to prevent the COVID-19 infection. [ABSTRACT FROM AUTHOR]

PURPOSE: The present study was undertaken to investigate the behavioral distribution pattern and progression of coronavirus disease 2019 (COVID-19) across age and gender in the state of Rajasthan, India, inherently distinctive and native to localized part of the globe giving requisite information and paraphernalia to designate advisory board of the state to design and frame customized policy for demands of the state as per the trending pattern relative to age and sex distribution, profile of new infected cases, recovery rate, and case fatality rate. METHODS: The present ongoing study assessed patients admitted till April 22, 2020, across the state of Rajasthan, India, with reverse transcriptase-polymerase chain reaction (RT-PCR)-confirmed COVID-19 test. Analyses of the patients included characteristic age and gender distribution through the geographic identities of state along with the time trending pattern of newly infected patients, recovered patients, and case fatality rate. RESULTS: A total of 1888 sample patient population of RT-PCR-confirmed COVID-19 was evaluated, with the majority of sample patient population being in young adult age group with a mean age of 34.42 years. Nearly 11.65% of the patients were below 15 years of age, 34.79% were in the age range of 16–30 years, 25.90% were in the age group of 31–45 years, and 17.69% were in the age group of 46–60 years, with only 9.95% of the patient population being in the age group of above 60 years. Interestingly, 11.65% of patients with COVID-19 were in the pediatric age group. The percent of affected females (37.35%) was much less than that compared to males (62.65%), with an average sex ratio of 0.59. Across the sample patient population of 1888, 543 patients recovered fully, 25 patients died, and 1320 cases were active in the said time frame, with an average recovery rate of 28.76% and a case fatality rate of 1.32%, and the remaining 69.91% of the patient population made up the active case group. The timeline and the trending pattern of COVID-19 in the state of Rajasthan was suggestive of an increasing rise of number of new cases with antecedent mortality, though a reassuring concomitant rise in the recovery rate of patients could also be appreciated. The infective COVID-19 dictum of spread through contact could very well be appreciated in select geographic hotspots and/or zones, and 108 sample patient population was from out of Rajasthan. CONCLUSION: It was interesting to observe that majority of the resident population of the state of Rajasthan that was COVID-19 positive was in the young adult age group of 30–50 years inclusive of pediatric patients, an observation that is different from reports as documented from across the world. Male population seemed to be more prone to infection. The time frame in which the evaluation was done is suggestive of an increasing trend in the number of new cases with antecedent case fatality, though recovery was also on the rise indicative of a potential decreasing load. The geographic mapping of COVID-19 patients could be established through contact tracing. [ABSTRACT FROM AUTHOR]