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Land subsidence (LS) is a global phenomenon that has affected several urban centres around the world such as Jakarta (Indonesia), Mexico City (Mexico), Xi'an (China), and Iron County (US). It has mainly been attributed to anthropogenic activities such as groundwater exploitation, especially in unconsolidated aquifer systems rich in highly compressible clay and silt. The platy clay minerals rearrange into horizontal stacks after dewatering, leading to a volume change due to overburden. In this study, land subsidence is investigated in the Quetta and Mastung districts, Balochistan, Pakistan, by employing Small Baseline Subset (SBAS) Interferometric Synthetic Aperture Radar (InSAR), Global Navigation Satellite System (GNSS), and groundwater level (GWL) variations. This study represents the first attempt in Pakistan to measure the long-term land subsidence by fusing GNSS and InSAR data for improved validity. InSAR data from the Sentinel-1 satellite in the Ascending (195 scenes) and Descending (183 scenes) tracks were used to analyse LS from December 2015 to December 2022. High-accuracy Trimble NetRS GNSS receivers were used in five locations from October 2006 to December 2022. An average subsidence ranging from 3.2 cm/y to 16 cm/y was recorded in the valley mainly due to the GWL decline and clay-rich sediments, which are prone to compaction due to dewatering. An accumulative LS of 2 m was recorded by the permanent GNSS station in central Quetta from October 2008 to January 2023 (14.2 years). An acceleration in the subsidence from 12 cm/y to 16.6 cm/y after 2016 was recorded by the continuous GNSS. Additionally, the InSAR and GNSS values were compared for validation, resulting in a good correlation between both techniques. A GWL decline ranging from 1.7 m to 6 m was recorded by the piezometers in Quetta during the period 1987–2022. Large- and small-scale fissures were observed in the study area during the surveys. These fissures are responsible for damage to the city's infrastructure and aquifer contamination. The subsidence profile also agrees with the subsurface lithology. Our assessment concludes that Quetta may be the fastest-sinking metropolitan city in Pakistan. The overexploitation of groundwater and the population explosion may be the main contributing factors for the land subsidence. [ABSTRACT FROM AUTHOR]