1. Esophageal body motility in people with diabetes: comparison with non-diabetic healthy individuals.
- Author
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Jorge JX, Panão EA, Simões MA, Borges CI, Delgado FJ, Coelho AC, Silva AL, and Almeida CC
- Subjects
- Case-Control Studies, Diabetes Mellitus, Type 2 epidemiology, Diabetes Mellitus, Type 2 physiopathology, Esophageal Motility Disorders complications, Esophageal Motility Disorders epidemiology, Female, Humans, Male, Middle Aged, Peristalsis, Portugal epidemiology, Reference Values, Diabetes Mellitus, Type 2 complications, Esophageal Motility Disorders physiopathology, Esophagus physiopathology, Manometry methods
- Abstract
Aims: The aim of this study was to compare esophageal motor characteristics between diabetics and healthy individuals., Methods: Esophageal manometry was performed in 34 type 2 diabetics and 32 healthy individuals. Waves were evaluated in the 3 thirds of the esophagus (P1=upper, P2=middle, and P3=distal)., Results: In diabetics vs. controls, wave distribution was as follows: peristaltic waves, 83.5 ± 22.2% vs. 96.3 ± 4.4%, p<0.002; simultaneous waves, 3.26 ± 5.8% vs. 0.53 ± 1.3%, p<0.01; no transmitted waves, 10.62 ± 20.7% vs. 2.75 ± 3.0%, p<0.002; and retrograde waves, 2.68 ± 4.0% vs. 0.31 ± 1.1%, p<0.03. Wave amplitude was similar between groups. Average upstroke (mmHg/s) in diabetics vs. non-diabetics was P2, 33.8 ± 13.9 vs. 40.2 ± 17.7, p<0.03; and P3, 29.8 ± 15.3 vs. 41.3 ± 14.0, p<0.002., Conclusions: (1) Simultaneous waves, no transmitted waves, and retrograde esophageal waves were significantly more frequent in diabetics. (2) Average upstroke was significantly lower within the middle and distal esophagus of diabetic individuals. (3) Wave amplitude was similar in both groups., (Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.)
- Published
- 2012
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