1. Screening of Fabry Disease in Patients with Chest Pain Without Obstructive Coronary Artery Disease.
- Author
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Hernández-Hernández A, Diez-López C, Azevedo O, Palomino-Doza J, Alfonso F, Fuentes-Cañamero ME, Mogollón Jiménez MV, Casanova Rodríguez C, Ruz A, Tirón C, Climent V, and Garcia-Pavia P
- Subjects
- Aged, Angina Pectoris diagnostic imaging, Computed Tomography Angiography, Coronary Angiography, Coronary Artery Disease diagnostic imaging, Cross-Sectional Studies, Fabry Disease diagnostic imaging, Female, Humans, Male, Middle Aged, Portugal epidemiology, Prevalence, Spain epidemiology, Angina Pectoris epidemiology, Coronary Artery Disease epidemiology, Fabry Disease epidemiology
- Abstract
Identification of Anderson-Fabry disease (AFD) in cardiac patients has been restricted so far to patients with left ventricular hypertrophy. Coronary microvascular dysfunction has been described in AFD with and without cardiac hypertrophy and may represent the only manifestation in AFD patients, offering a possible earlier diagnosis. We studied the prevalence of AFD in 663 patients with chest pain with normal or non-obstructive coronary arteries. The overall prevalence of AFD in this cohort was only 0.15% (1/663). AFD is not a frequent cause of chest pain without obstructive coronary artery disease and screening efforts should not be conducted in this patient population., (© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC part of Springer Nature.)
- Published
- 2021
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