1. Markers of metabolic syndrome in obese children before and after 1-year lifestyle intervention program.
- Author
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Pedrosa, C., Oliveira, B., Albuquerque, I., Simões-Pereira, C., Vaz-de-Almeida, M., and Correia, F.
- Subjects
OBESITY treatment ,METABOLIC syndrome risk factors ,ADOLESCENCE ,ANALYSIS of variance ,ANTHROPOMETRY ,APOLIPOPROTEINS ,BEHAVIOR modification ,BLOOD testing ,BLOOD pressure measurement ,C-reactive protein ,CHI-squared test ,CHILDREN'S health ,CHILD nutrition ,CHOLESTEROL ,CLINICAL trials ,STATISTICAL correlation ,EXERCISE ,EXERCISE therapy ,FACTOR analysis ,HEALTH behavior ,HIGH density lipoproteins ,LONGITUDINAL method ,NUTRITION education ,HEALTH outcome assessment ,PARENTS ,RESEARCH funding ,STATISTICAL sampling ,STATISTICS ,T-test (Statistics) ,TRIGLYCERIDES ,U-statistics ,STATISTICAL power analysis ,DATA analysis ,STATISTICAL significance ,BODY mass index ,TREATMENT effectiveness ,PRE-tests & post-tests ,REPEATED measures design ,DATA analysis software ,CHILDREN - Abstract
Purpose: Excess weight may be related to the development of adverse cardiometabolic risk factors in children. The aim of this study was to evaluate the effect of a lifestyle intervention program (nutrition and exercise counseling) on anthropometric parameters and metabolic syndrome (MS) components in Portuguese overweight/obese children. Methods: A total of 83 overweight/obese children aged 7-9 years were assigned to a 1-year individual or group-based treatment (GT); 61 children (z-score BMI (zBMI): 1.93 ± 0.28; 27 boys and 34 girls) completed the program. Anthropometric and biochemical parameters were assessed at baseline, at 6 months and at 1 year. Results: The overweight/obese children, compared to normal-weight ones, presented significantly higher blood pressure, total-cholesterol, total-cholesterol/high density lipoprotein cholesterol (HDL) ratio, triglycerides, Apolipoprotein B and C-reactive protein levels, while HDL and Apolipoprotein A-I were significantly lower. At baseline, the prevalence of MS was 16.4% in overweight/obese and 0% in normal-weight children. The number of components of MS was significantly higher in children with higher zBMI. Lifestyle intervention led to a significant improvement in zBMI, waist circumference/height ratio, HDL, triglycerides, Apolipoprotein A-I, and Apolipoprotein B levels. The prevalence of MS decreased to 14.8%. The GT intervention seems to be more successful, with a significant decrease in zBMI and an increase in HDL and a lower drop-out rate. Conclusions: Overweight/obese children have multiple risk factors associated with the MS. Lifestyle intervention, both individual and group-based treatment, led to an improvement in the degree of overweight/obesity and in MS components. [ABSTRACT FROM AUTHOR]
- Published
- 2011
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