1. Hyperbaric oxygen (HBO) therapy as an effective therapeutic option for patients with severe idiopathic sudden sensorineural hearing loss.
- Author
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Ahn J. H., Kang W. S., Park H. J., and Chung J. W.
- Subjects
TREATMENT of hearing disorders ,DEAFNESS ,HYPERBARIC oxygenation ,CONFERENCES & conventions - Abstract
Backgrounds: Idiopathic sudden sensorineural hearing loss (ISSNHL) is one of the diseases whose mechanism is not fully understood and is not yet fully cured. As one of convincing etiology of ISSNHL is cochlear ischemia, HBO therapy is suggested to be a promising treatment for hearing recovery, especially for the patients with severe hearing loss (over 70 dB). Objectives: The aim of this study is to demonstrate the effectiveness of HBO therapy for patients with ISSNHL who showed severe hearing loss. Methods: We retrospectively reviewed the medical records of patients who were diagnosed with ISSNHL at Asan medical center from January 2016 to December 2017. All the patients enrolled in this study showed over 70 dB HL on the affected ears. Patients in HBO group received HBO therapy 14 times with systemic and intratympanic steroid therapy, while patients in control group received only systemic and intratympanic steroid therapy. Results: Total 82 patients (83 ears) were enrolled in this study. 37 patients (38 ears) were enrolled for HBO group and 45 patients (45 ears) were enrolled for control group. There were no differences in baseline parameter between two groups; gender, age, affected side, combined symptoms such as tinnitus and dizziness, initial glucose level and initial hearing. After 2-weeks treatment, HBO group showed significantly improved hearing than control group (28.1±26.9 dB in HBO group and 14.8±13.5 dB in control group in W4FA, p<0.05), especially in low frequency (0.5 kHz, 1 kHz, 2 kHz, p<0.05). Conclusions: From this study, we strongly recommend HBO therapy as initial treatment option for ISSNHL patients who suffer from severe hearing loss or as salvage treatment option for patients who failed from initial steroid treatment. [ABSTRACT FROM AUTHOR]
- Published
- 2022