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As a consequence of the global health emergency in early 2020, universities had to tackle a sudden shift in their teaching--learning strategies so that the preset competences could be fulfilled. This study presents the learning outcomes of the implemented tasks, student experiences, and feedback, as well as some reflections from the instructors with a holistic perspective of the courses due to the adopted measures and adaptations. Six courses taught at civil engineering degrees of three universities, two from Spain and one from Peru, were analyzed. The teaching and evaluation strategies are described, and some reflections are made by comparing the student's performance with the previous course. Though the shift to online learning had to be made from day to day, with no time for preparation, the experience has proved that online learning can be beneficial in some aspects and has probably come to stay, although some other aspects are difficult to replace with respect to face-to-face learning, especially students' engagement and motivation. The significance of this study relies on a description of the challenges that arose due to the global public health and an assessment of the results of the implemented strategies to account for both teaching and evaluation in modules of civil engineering. After the acquired experience, new questions have arisen, e.g., what type of content is (and what is not) adequate or suitable for online exams? What features have come to stay? Has higher education taken a step forward to tomorrow's education?

The classroom closure during the first semester of 2020 entailed decisive changes in higher education. Universities have become more digital in both the availability of e-resources and pervasive devices and how students communicate with lecturers and classmates. Learners adapted their study habits with a growing role of self-paced, internet-based strategies. Some flipped learning approaches have proven their efficacy under the remote-teaching physical constraints. This study aimed to appraise the outcomes from the implementation of various web-based, learning-aid tools on flipped teaching approaches in engineering modules. The open educational resources (OER) performed satisfactorily during the lockdown period in three universities from two countries with similar higher education models. Such resources encompassed classroom response systems and web-based exercise repositories, designed for diverse purposes such as autonomous learning, self-correction, flipped classroom, peer assessment, and guided study. The acquired experiences reveal that OER helped students to enhance their engagement, reach the deeper levels of the cone of learning, and widen their range of learning abilities. This procedure is easily attainable for architecture, engineering, and construction (AEC) courses and lifelong learning settings. Feedback from students, instructors' perceptions, and learning outcomes show the suitability and effectiveness of the web-based learning assistant procedure presented here.

Purpose: The study of sustainability within universities is recognized as essential for debates and research; in the long term, the "sustainable university" concepts can contribute to sustainability from a larger perspective. This study aims to propose a conceptual model for evaluating the students' sustainability considering their interactions with the university and the environment. The proposed model is titled Sunshine model. It is applied to students of the La Salle University, Peru. Design/methodology/approach: The model combines academic performance, happiness and the ecological footprint to quantify university students' sustainability. A structured questionnaire survey was elaborated and applied to get the raw data that feeds the three methods. The students' average grades evaluate academic performance. Happiness is quantified by the happiness index method, and the ecological footprint is measured by the demand for food, paper, electricity, transport and built-up areas. Results are evaluated under both approaches, overall group performance and clusters. Findings: The proposed model avoids misleading interpretations of a single indicator or discussions on sustainability that lack a conceptual model, bringing robustness in assessing students' sustainability in universities. To have a low ecological footprint, the student needs to need up to 1 planet for their lifestyle, be considered happy with at least 0.8 (of 1) for happiness index, and have good academic performance with at least a grade of 7 (of 10) in their course. Regarding the case study, La Salle students show a high academic grade degree of 7, a high level for happiness index of 0.8 and low performance for ecological footprint by demanding 1.8 Earth planets, resulting in an "environmentally distracted" overall classification for students with 2019 data. From a cluster approach, 81% of evaluated students (n = 603) have low performance for ecological footprint, whereas 31% have low performance for indicators of recreational activities of happiness. Changing lifestyles and making more recreational activities available play crucial roles in achieving higher sustainability for the La Salle students. Research limitations/implications: The happiness assessment questionnaire can be subject to criticism, as it was created as a specific method for this type of audience based on existing questionnaires in the literature. Although it can be seen as an important approach for diagnoses, the proposed model does not consider the cause-effect aspect. The decision-maker must consider the sociocultural aspects before implementing plan actions. Practical implications: University managers can better understand why university students have high or low sustainability performance and provide more effective actions toward higher levels of students' sustainability. Originality/value: The proposed model, Sunshine model, overcomes the single-criteria existing tools that access the sustainability of universities. Rather than focusing on university infrastructure, the proposed model focuses on the students and their relationship with the university.

This article focuses on Brazil and Peru, the Latin American epicenter of the coronavirus pandemic during 2020 and 2021. The pandemic magnified the legacy of years of neoliberal policies, corruption and racism in these countries, the limitations of their poverty-reduction programs, the fragility of their democratic systems, and the insufficient political regard for public health and basic sanitation. I rely on the concepts of negligence and necropolitics. The first refers to the abdication of authorities in providing sufficient basic services to its citizens. The second — coined by Achille Mbembe before the pandemic — is used to explain the banalization by governments of preventable deaths of discriminated social groups. On a global level, the problematic access to medical equipment and vaccines was a failure because of the hoarding of vaccines by rich nations and the blaming of developing countries for their high mortality. The result was that national and international governmental reactions to COVID-19 worsened health asymmetries within countries and between the Global North and South. [ABSTRACT FROM AUTHOR]

A quarter of humanity is estimated to have been exposed to Mycobacterium tuberculosis (Mtb) with a 5–10% risk of developing tuberculosis (TB) disease. Variability in responses to Mtb infection could be due to host or pathogen heterogeneity. Here, we focused on host genetic variation in a Peruvian population and its associations with gene regulation in monocyte-derived macrophages and dendritic cells (DCs). We recruited former household contacts of TB patients who previously progressed to TB (cases, n = 63) or did not progress to TB (controls, n = 63). Transcriptomic profiling of monocyte-derived DCs and macrophages measured the impact of genetic variants on gene expression by identifying expression quantitative trait loci (eQTL). We identified 330 and 257 eQTL genes in DCs and macrophages (False Discovery Rate (FDR) < 0.05), respectively. Four genes in DCs showed interaction between eQTL variants and TB progression status. The top eQTL interaction for a protein-coding gene was with FAH, the gene encoding fumarylacetoacetate hydrolase, which mediates the last step in mammalian tyrosine catabolism. FAH expression was associated with genetic regulatory variation in cases but not controls. Using public transcriptomic and epigenomic data of Mtb-infected monocyte-derived dendritic cells, we found that Mtb infection results in FAH downregulation and DNA methylation changes in the locus. Overall, this study demonstrates effects of genetic variation on gene expression levels that are dependent on history of infectious disease and highlights a candidate pathogenic mechanism through pathogen-response genes. Furthermore, our results point to tyrosine metabolism and related candidate TB progression pathways for further investigation. Author summary: Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is a leading cause of mortality globally. Mtb-exposed individuals have heterogeneous outcomes following infection with Mtb, where some progress to TB, while many remain asymptomatic. We hypothesized that genetic variation could partly explain risk of TB, by regulating the expression of genes involved in the control of Mtb infection. In this study in Peru, we recruited former TB patients and Mtb-exposed household contacts of TB patients who remained asymptomatic to define how genetic variation regulates expression of genes in the innate immune system. We identified 4 genetic variants that have different effects on gene expression based on the TB history of the participant. The lead variant regulated expression of a key enzyme (Fumarylacetoacetate Hydrolase; FAH) in tyrosine catabolism. Knocking out the gene in myeloid cells increased susceptibility to Mtb infection. The results implicate FAH as a candidate host factor involved in TB progression. [ABSTRACT FROM AUTHOR]

In Peru, confined masonry houses are self-built, which makes it crucial to determine their seismic vulnerability. The objective of the research was to estimate the seismic vulnerability of confined masonry dwellings in the Pueblo Libre-Jaén sector using assembly algorithms. A database was constructed with data obtained from the National Institute of Civil Defense (INDECI), scientific articles, and theses. Subsequently, the data set was divided into a training set (80%) and a validation set (20%), employing the stacking method with five combinations CB_1, CB_2, CB_3, CB_4, and CB_5. The basic algorithms Gradient-Boosting, Random-Forest, Extra-Tree, and Decision-Tree were utilized as the base algorithms, with the final estimator being the Random Forest Meta-Learner. The models were trained and validated in Python, achieving accuracies of 94.95, 95.48, 95.39, and 95.66 for the base models and 95.62, 95.23, 95.76, 95.90, and 94.80% for the ensemble models. The most accurate models were the simple Gradient Boosting (95.66%) and the assembled models CB_3 (95.76%) and CB_4 (95.90%). The CB_4 model, which is composed of the Decision Tree and Gradient Boosting algorithms, was applied to the Pueblo Libre sector and yielded a reliability estimate of greater than 95% for the seismic vulnerability of confined masonry. This estimate was classified as high (1.48%), moderate (32.85%), and low (65.67%). It is anticipated that the model implemented will enable engineers and authorities to implement mitigation measures to reinforce housing in the event of a seismic event. [ABSTRACT FROM AUTHOR]

Peropteryx pallidoptera is the newest described species of Peropteryx, know from only few localities in Ecuador, Peru, Brazil, Colombia, and Bolivia. Herein, we report new records of this species, and we show that P. pallidoptera has a wider distribution than known across the Amazon. Our records are based on field sampling and, mostly, on museum vouchers, which reinforces the importance of biological collections and the need to continually review deposited specimens. [ABSTRACT FROM AUTHOR]

There is a constant search for alternative food sources due to rapid population growth and nutritional problems that affect the world. In this context, edible insects such as the Acheta domesticus (a species of cricket with a high protein and fat content) have become an alternative food source and managed to capture the attention of researchers due to their valuable nutritional content and low environmental impact. This study aimed to identify and characterize the variables and strategic actors that lead the flour production market based on the aforementioned Acheta domesticus in Peru. A structural analysis of descriptive scope was conducted with the help of a panel of five experts knowledgeable about the sector in question and the Cross Impact Matrix and Multiplication Applied to Classification (MICMAC) tool to pursue consensus by motivating collective reflection. The findings revealed that the market studied presents an unstable dynamic, which implies a dispersion of the variables along the bisector since it has eight key variables in total, technological development and profitability being the most sensitive; At the same time, on the side of the social actors, the insect producers are the ones who predominate among the others. This study constitutes a starting point for any strategic action linked to the planning and developing of new alternative sources that seek a change in the studied market. [ABSTRACT FROM AUTHOR]

The objective of this study was to propose a teacher training program based on the flipped classroom model with MOOCs to strengthen access to information and information literacy among primary education teachers in the Lambayeque region of Peru. The non-experimental design was assumed with a quantitative approach and a propositional, descriptive type. A diagnosis was made using a questionnaire given to 917 primary school teachers. It was discovered that nearly all of the items in the questionnaire revealed a deficiency in the ability to navigate, search, and filter information, data, and digital content; the highest percentages were at the Basic level, with the exception of the item expressing information needs in an organized manner, which was at the Advanced C2 level. The lowest percentage was at the Advanced C1 level, and the majority of the lower percentages were at the Advanced level. In addition, there are competency deficiencies in the evaluation of information, data, and digital content of nearly all the items: the highest percentages were at the Basic level, with the exception of the item involving the processing of information, data, and digital content, where 26.4% were at the Intermediate B1 level and just 2.8% managed to be at the highest level, which is Advanced C2. Furthermore, when it came to storage and retrieval of information, data, and digital content competency, all the high percentages were at the Basic level, and all the low percentages were at the highest level, that is, Advanced. These findings helped us to understand that teachers have only a basic knowledge of information literacy and information competency. As a result, it is necessary to advocate for a teacher training program based on the flipped classroom model with MOOCs. This idea was supported by the opinions of five experts, who stated that its implementation would enable primary teachers of Regular Basic Education in the region of Lambayeque (Peru) to develop their access to information and information literacy competency area. [ABSTRACT FROM AUTHOR]

This paper presents an experimental campaign conducted next to the Condoroma dam, in Perú, at 4075 m a.s.l. The tests carried out in this paper were conducted in a 21 m long channel located at the toe of Condoroma dam. The setup consisted of a series of standard profile spillways with a vertical upstream face of up to five different dimensionless heights (P/Hd) ranging from 0.5 to 2. The experimental results indicated that, the P/Hd ratio influences the discharge coefficients in Condoroma, and P/Hd ≥ 1 values are recommended for the design of the spillway profile. In addition, for all the P/Hd ratios studied, the discharge coefficients adjusted to the Condoroma altitude were lower than those reported by classical formulations used in conventional spillway designs. Finally, a generalized equation is proposed to estimate the discharge coefficient for standard spillways located in dams at similar elevations above sea level. [ABSTRACT FROM AUTHOR]

This study analyzed the impact of leachate from a temporary landfill on soil microbial diversity in Tingo María, Huánuco region, Peru. Three treatments were used: untreated soil (S), addition of stream water (T0), leachate (T1), and leachate treated by coagulation and flocculation (T2), with 828.5 ml/week added in three weekly doses. Soil samples were collected from the Reserved Forest of the Universidad Nacional Agraria de la Selva. Twenty-one randomly distributed soil samples were taken and homogenized for analysis. Soil quality parameters measured included sand, clay, silt, texture, pH, organic matter, nitrogen, phosphorus and potassium. As for microorganisms, viable aerobes, lactobacilli, actinomycetes, fungi, nitrogen-fixing bacteria, and Escherichia coli were quantified using specific culture and counting methods for each of them. To evaluate the impact of the leachate on microbial diversity, equity indices (Shannon and inverse Simpson), dominance indices (complementary Simpson and Berger Parker) and the percentage composition of each microorganism per treatment were used. An ANOVA was performed to estimate differences in microbial diversity, with a Tukey test at a significance level of α = 0.05. The study showed that leachates affect soil microbial diversity, reducing equity and increasing the dominance of certain species such as E. coli. They also alter physicochemical parameters, decreasing organic matter and nitrogen but increasing other elements such as phosphorus and potassium. This could have implications for soil health and functionality. [ABSTRACT FROM AUTHOR]

Biodiversity conservation is a complex and transdisciplinary problem that requires engagement and cooperation among scientific, societal, economic, and political institutions. However, historical approaches have often failed to bring together and address the needs of all relevant stakeholders in decision‐making processes. The Tropical Andes, a biodiversity hotspot where conservation efforts often conflict with socioeconomic issues and policies that prioritize economic development, provides an ideal model to develop and implement more effective approaches. In this study, we present a co‐design approach that mainstreams and improves the flow of biodiversity information in the Tropical Andes, while creating tailored outputs that meet the needs of economic and societal stakeholders. We employed a consultative process that brought together biodiversity information users and producers at the local, national, and regional levels through a combination of surveys and workshops. This approach identified priority needs and limitations of the flow of biodiversity information in the region, which led to the co‐design of user‐relevant biodiversity indicators. By leveraging the existing capacities of biodiversity information users and producers, we were able to co‐design multiple biodiversity indicators and prioritize two for full implementation ensuring that the data was findable, accessible, interoperable, and reusable based on the FAIR (Findable, Accessible, Interoperable, and Reusable) principles. This approach helped address limitations that were identified in the stakeholder engagement process, including gaps in data availability and the need for more accessible biodiversity information. Additionally, capacity‐building workshops were incorporated for all producers of biodiversity information involved, which aimed to not only improve the current flow of biodiversity information in the region but also facilitate its future sustainability. Our approach can serve as a valuable blueprint for mainstreaming biodiversity information and making it more inclusive in the future, especially considering the diverse worldviews, values, and knowledge systems between science, policy, and practice. [ABSTRACT FROM AUTHOR]

Copyright of World Water Policy is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Corydoras multiradiatus (Orcés V.1960), commonly called "hog-nosed brochis" and popularly known in Peru as "coridora jumbo" is a species of commercial importance among the Amazonian ornamental fish. It is known that the integrity of the health of aquatic organisms positively increases the production and trade of quality products, however, the opposite negatively affects financial losses and production costs. Among the possible diseases, parasitism stands out, and there is still a lack of information, mainly about metazoans, parasitic species that infect C. multiradiatus. Therefore, this study aimed to identify the species of endoparasite metazoans in C. multiradiatus and evaluate the histological lesions present to provide information to ornamental fish producers about these pathologies. Thirty specimens of C. multiradiatus were collected by fishermen in the municipality of "Belén" in Iquitos, Peru. The results revealed the presence of Tylodelphys sp. and nematode larvae in the intestinal wall and Procamallanus (Spirocamallanus) pintoi (Kohn & Fernandes 1988) present in the intestine. The histopathological analysis of the intestine showed several lesions: necrosis; cell desquamation; infiltration of lymphocytes in the mucosa; transepithelial infiltration of lymphocytes; enterocyte hyperplasia; goblet cell hyperplasia and enterocyte desquamation. The study revealed the presence of endoparasites in C. multiradiatus collected in Iquitos, Loreto-Peru, and a moderate degree of damage caused by histological lesions in the intestine of infected fish. The results of this work will serve the fishermen, collectors and aquarists of the city of Iquitos, who, knowing the endoparasites present in C. multiradiatus and the damage they can cause to the fish, will be able to adopt prophylactic measures in order to guarantee the good condition of the fish for its consequent commercialization at a local, national and international level. [ABSTRACT FROM AUTHOR]

Objective: To investigate the perinatal outcomes in Brazilian, Peruvian, and Colombian women in a Brazilian reference maternity hospital based at Amazon triple border region. Method: A cross-sectional case study of data from 3242 live birth certificates issued at the Tabatinga public maternity hospital, in the countryside of Amazonas, in the period between January 2015 and December 2017. Maternal and perinatal independent variables were analysed based on central tendency and variability, and frequency distribution for categorical variables. The Pearson's Chi-Square test and univariate analyses were performed to estimate probability ratios (Odds Ratio-OR). Results: Significant differences were found in the education level in the three population groups, as well as in the number of previous pregnancies, antenatal consultations, month of initial prenatal care, and type of delivery. Brazilian pregnant women had more prenatal consultations, caesarean sections, and premature births. Peruvian and Colombian women started antenatal care later, and those with high-risk pregnancies tended to deliver in their home country. Conclusion for Practice: Our findings show some singularities in the care of women and infants in the Amazonian triple border region. The Brazilian Unified Health Care System performs an important role in the guarantee of free access to health services, and ensures comprehensive care for women and infants, promoting human rights in border regions regardless of nationality. Significance: The triple frontier between Brazil, Colombia, and Peru is a region that has specificities that defy assistance flows, normally based on predominantly urban and locally fixed populations. Analysis of the live birth certificate data completed after the births that took place in the only public maternity hospital in this region could help to quantify and understand the migratory phenomenon and its repercussions on the health of women and their infants. Studies show that maternal and child mortality indicators are sensitive to health conditions and can reveal various aspects of a territory, such as social inequalities, socioeconomic development, and quality of life. [ABSTRACT FROM AUTHOR]

Copyright of Revista de la Facultad de Medicina Humana is the property of Instituto de Investigaciones en Ciencias Biomedicas de la Universidad Ricardo Palma and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Peruana de Investigación Materno Perinatal is the property of Peruvian Journal of Maternal Perinatal Research / Revista Peruana de Investigacion Materno Perinatal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Peru is an emerging nation with a nonuniform development where the growth is focused on some specific cities and districts, as a result there is serious economic inequalities across the country. Despite the poverty in Peru has declined in the last decades, there is still poor districts in risk to become extremely poor, even in its capital, Lima. In this context, it is relevant to study the incidence of extreme poverty at district levels. In this paper, we propose to estimate the quantiles of the incidence of extreme poverty of districts in Lima by using spatial quantile models based on the Kumaraswamy distribution and spatial random effects for areal data. Furthermore, in order to deal with spatial confounding random effects we used the Spatial Orthogonal Centroid "K"orrection approach. Bayesian inference for these hierarchical models is conveniently performed based on the Hamiltonian Monte Carlo method. Our modeling is flexible and able to describe the quantiles of incidence of extreme poverty in Lima. [ABSTRACT FROM AUTHOR]

Copyright of Revista Científica de Enfermería (2071-5080) is the property of Colegio de Enfermeros del Peru and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista de Ciencias Sociales (13159518) is the property of Revista de Ciencias Sociales de la Universidad del Zulia Venezuela and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Peruana de Investigación Materno Perinatal is the property of Peruvian Journal of Maternal Perinatal Research / Revista Peruana de Investigacion Materno Perinatal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The purpose of this research is to describe the incidence and impact of the Educational Model that is applied in the Rural Training Centers in Alternation (CRFA). We try to answer how young people and adolescents of the Shawi-Perú Amazonian indigenous community value the functionality of learning at work. The information is collected through three categories; the first, making known the integration, transformation, and functionality of the knowledge acquired by the students; the second, the repercussion and concretion of the new knowledge in the Shawi families and the third, the contribution of the CRFA to the development and improvement of the quality of life of the Shawi community. The methodology is quantitative; the population is made up of students, former students, pedagogical staff, and collaborators. The applied instrument consisted of 41 indicators, whose Cronbach's Alpha parameter yielded a reliability of 0.957; likewise, the Kolmogorov-Smirnov test was applied, identifying that the sample does not follow a normal distribution; therefore, to analyze the information obtained from the four educational agents, the non-parametric Kruskal-Wallis and Mann-Whitney U tests were applied. The results indicate that learning contributes to improving the quality of life of families and the sustainable development of the Shawi community. [ABSTRACT FROM AUTHOR]

There are nearly 7 million nursing professionals in the Region of the Americas, representing more than 56% of human health resources. The regulation of professional practices promotes and protects professional integrity, ensuring professionals are competent and well qualified. The Forum on Nursing Practice Regulation in the Region of the Americas aimed to present the regulatory frameworks for the professional practice of nursing; discuss strategic actions to support professional regulatory bodies; analyze requirements for licensing and renovating licenses; and share successful experiences in nursing regulation. The Forum counted on the participation of 83 guests in-person, with representatives from 17 countries from Latin America and the Caribbean. The COFENplay platform registered the participation of 6,906 spectators. The debates in the event led to the proposal of the following recommendations: promote a national discussion with key-actors, including the Ministries of Health, Education, and Work and Employment, to advance regulation in the countries; recommend an intersectoral articulation with the topic of Human Health Resource regulation; generate a common base for the identification of information on regulation; and broaden the research about these topics, as well as the ability to generate and analyze data. [ABSTRACT FROM AUTHOR]

Public management in Peru has serious shortcomings, especially in the field of human resources. It is a priority to resume the processes of improvement in order to move towards a modern state that serves the citizen. The COVID 19 pandemic continues to wreak havoc in the country. Many of the problems that have arisen as a result of the pandemic could have been addressed much more satisfactorily if the State had better management skills. Public management means the ability to correctly and efficiently manage state resources in order to meet the needs of citizens. While one of the issues that citizens complain about most is the various procedures one has to do to access a public service, they consider that there is a lot of bureaucracy and that it prevents their needs from being met. Therefore, this article discusses the impact of implementation of the latest reform policies on the service provided by the public sector in our country. To identify the extent to which the modernization of public management has led to a higher quality of service provided in state institutions. [ABSTRACT FROM AUTHOR]

Copyright of Enfermagem em Foco is the property of Conselho Federal de Enfermagem and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introduction: The HIV epidemic continues to disproportionately impact Latin‐American transgender women (TGW). We assessed factors associated with long‐term pre‐exposure prophylaxis (PrEP) engagement and adherence among TGW enrolled in the Implementation of PrEP (ImPrEP) study, the largest PrEP demonstration study in Latin America. Methods: HIV‐negative TGW aged ≥18 years reporting 1+eligibility criteria in the 6 months prior to enrolment (e.g. sex partner known to be living with HIV, condomless anal sex [CAS], transactional sex or having a sexually transmitted infection [STI]) who could safely take PrEP were enrolled. Follow‐up visits were conducted at 4 weeks and then quarterly. We conducted logistic regression to identify factors associated with long‐term PrEP engagement (3+ follow‐up visits in 52 weeks) and complete self‐reported adherence (no missed pills in the past 30 days) during follow‐up. For both outcomes, we constructed multivariable models controlling for country, socio‐demographics, sexual behaviour, substance use, STIs and self‐reported adherence at 4 weeks (long‐term engagement outcome only). Results: From March 2018 to June 2021, ImPrEP screened 519 TGW, enrolled 494 (Brazil: 190, Mexico: 66 and Peru: 238) and followed them for 52 weeks. At baseline, 27.5% of TGW were aged 18–24 years, 67.8% were mixed‐race and 31.6% had >secondary education. Most, 89.9% reported CAS, 61.9% had >10 sex partners and 71.9% reported transactional sex. HIV incidence was 1.82 cases per 100 person‐years (95% confidence interval [CI]: 0.76–4.38). Almost half of TGW (48.6%) had long‐term PrEP engagement, which was positively associated with reporting complete adherence at week 4 (aOR:2.94 [95%CI:1.88–4.63]) and was inversely associated with reporting CAS with unknown‐HIV partner (aOR:0.52 [95%CI:0.34–0.81]), migration (aOR:0.54 [95%CI:0.34–0.84]), and being from Mexico (aOR:0.28 [95%CI:0.14–0.53]). Self‐reported adherence was associated with TGW aged >34 (aOR:1.61 [95%CI:1.10–2.34]) compared to those aged 25–34 and those with >secondary education (aOR:1.55 [95%CI:1.10–2.19]) and was lower among TGW from Peru (aOR:0.29 [95%CI:0.21–0.41]) or reporting PrEP‐related adverse effects (aOR:0.63 [95%CI:0.42–0.92]). Conclusions: Although TGW were willing to enrol in ImPrEP, long‐term PrEP engagement and complete self‐reported adherence were limited, and HIV incidence remained relatively high. A successful HIV prevention agenda should include trans‐specific interventions supporting oral PrEP and exploring long‐acting PrEP strategies for TGW. [ABSTRACT FROM AUTHOR]

Mine tailings are produced by mining activities and contain diverse heavy metal ions, which cause environmental problems and have negative impacts on ecosystems. Different microorganisms, including yeasts, play important roles in the absorption and/or adsorption of these heavy metal ions. This work aimed to analyze proteins synthesized by the yeast Yarrowia lipolytica AMJ6 (Yl-AMJ6), isolated from Andean mine tailings in Peru and subjected to stress conditions with common heavy metal ions. Yeast strains were isolated from high Andean water samples impacted by mine tailings from Yanamate (Pasco, Peru). Among all the isolated yeasts, the Yl-AMJ6 strain presented LC50 values of 1.06 mM, 1.42 mM, and 0.49 mM for the Cr+6, Cu+2, and Cd+2 ions, respectively. Proteomic analysis of theYl-AMJ6 strain under heavy metal stress showed that several proteins were up- or downregulated. Biological and functional analysis of these proteins showed that they were involved in the metabolism of proteins, nucleic acids, and carbohydrates; response to oxidative stress and protein folding; ATP synthesis and ion transport; membrane and cell wall; and cell division. The most prominent proteins that presented the greatest changes were related to the oxidative stress response and carbohydrate metabolism, suggesting the existence of a defense mechanism in these yeasts to resist the impact of environmental contamination by heavy metal ions. [ABSTRACT FROM AUTHOR]

Copyright of Archivos de Cardiología de México is the property of Publicidad Permanyer SLU and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Científica de Enfermería (2071-5080) is the property of Colegio de Enfermeros del Peru and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This article analyzes how the Peruvian doctors Carlos Enrique Paz Soldán and Juan B. Lastres were intermediaries in the circulation, transfer and adaptation of the knowledge produced by historians of medicine from Perú, through the United States and Europe. These efforts were part of the conviction that medical humanism would train physicians with empathy for their patients and that past Peruvian medical practices had to be part of universal history. This allowed Peruvians to participate, at least for some time, in the medical history international network. [ABSTRACT FROM AUTHOR]

Purpose: A university community that works for and supports students along their developmental trajectory through responsible leadership is important for a sustainable and accountable educational environment. Public and private institutions differ in their student leadership responsibilities. In light of this, the objective of this study is to analyze the level of responsible leadership between public and private colleges in Peru in 2022. Design/Methodology/Approach: This study employs quantitative and descriptive-comparative research methods. This study's sample included 459 instructors from six public and private institutions in Peru. The survey-based method was used to collect data on responsible education leadership. Findings: The study's findings emphasized the importance of responsible leadership in colleges. This study shows that private institutions in Peru have a better level of responsible leadership than governmental universities. Practical Implications: This study underlines that strong leadership should always seek innovation in the field of education, keeping current with the most recent achievements and collecting feedback from university teachers and students. To obtain a higher education level, institutions should therefore foster responsible leadership. Originality/value: This research contributes to a previously unexplored section of the literary canon. Several prior studies have researched responsible leadership; however, the context of the present study is neglected by those prior studies. Previous research neglected the significance of responsible leadership within universities. Rarely have past studies compared national universities in Peru to private ones. Therefore, this work made a substantial contribution to the corpus of knowledge. [ABSTRACT FROM AUTHOR]

A major challenge remains to understand the relative contributions of history, dispersal, and environmental filtering to the assembly of hyperdiverse communities across spatial scales. Here, we examine the extent to which biogeographical history and habitat specialization have generated turnover among and within lineages of Amazonian trees across broad geographic and environmental gradients. We replicated standardized tree inventories in 102 0.1‐ha plots located in two distant regions—the western Amazon and the eastern Guiana shield. Within each region, we used a nested design to replicate plots on contrasted habitats: white‐sand, terra firme, and seasonally flooded forests. Our plot network encompassed 26,386 trees that together represented 2,745 distinct taxa, which we standardized across all plots and regions. We combined taxonomic and phylogenetic data with detailed soil measurements and climatic data to: (1) test whether patterns of taxonomic and phylogenetic composition are consistent with recent or historical processes, (2) disentangle the relative effects of habitat, environment, and geographic distance on taxonomic and phylogenetic turnover among plots, and (3) contrast the proportion of habitat specialists among species from each region. We found substantial species turnover between Peru and French Guiana, with only 8.8% of species shared across regions; genus composition remained differentiated across habitats and regions, whereas turnover at higher taxonomic levels (family, order) was much lower. Species turnover across plots was explained primarily by regions, but also substantially by habitat differences and to a lesser extent by spatial distance within regions. Conversely, the composition of higher taxonomic levels was better explained by habitats (especially comparing white‐sand forests to other habitats) than spatial distance. White‐sand forests harbored most of the habitat specialists in both regions, with stronger habitat specialization in Peru than in French Guiana. Our results suggest that recent diversification events have resulted in extremely high turnover in species and genus composition with relatively little change in the composition of higher lineages. Our results also emphasize the contributions of rare habitats, such as white‐sand forests, to the extraordinary diversity of the Amazon and underline their importance as conservation priorities. [ABSTRACT FROM AUTHOR]

This paper addresses an important debate in Amazonian studies; namely, the scale, intensity, and nature of human modification of the forests in prehistory. Phytolith and charcoal analysis of terrestrial soils underneath mature tierra firme (nonflooded, nonriverine) forests in the remote Medio Putumayo-Algodón watersheds, northeastern Peru, provide a vegetation and fire history spanning at least the past 5,000 y. A tree inventory carried out in the region enables calibration of ancient phytolith records with standing vegetation and estimates of palm species densities on the landscape through time. Phytolith records show no evidence for forest clearing or agriculture with major annual seed and root crops. Frequencies of important economic palms such as Oenocarpus, Euterpe, Bactris, and Astrocaryum spp., some of which contain hyperdominant species in the modern flora, do not increase through prehistoric time. This indicates pre-Columbian occupations, if documented in the region with future research, did not significantly increase the abundance of those species through management or cultivation. Phytoliths from other arboreal and woody species similarly reflect a stable forest structure and diversity throughout the records. Charcoal 14C dates evidence local forest burning between ca. 2,800 and 1,400 y ago. Our data support previous research indicating that considerable areas of some Amazonian tierra firme forests were not significantly impacted by human activities during the prehistoric era. Rather, it appears that over the last 5,000 y, indigenous populations in this region coexisted with, and helped maintain, large expanses of relatively unmodified forest, as they continue to do today. [ABSTRACT FROM AUTHOR]

Copyright of Biomédica: Revista del Instituto Nacional de Salud is the property of Instituto Nacional de Salud of Colombia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Extreme environments Morrope and Bayovar Salt lagoons, several ecosystems and microhabitats remain unexplored, and little is known about the diversity of Actinobacteria. We suggest that the endemic bacteria present in this extreme environment is a source of active molecules with anticancer, antimicrobial, and antiparasitic properties. Using phenotypic and genotypic characterization techniques, including 16S rRNA sequencing, we identified these bacteria as members of the genera Streptomyces, Pseudonocardia, Staphylococcus, Bacillus, and Pseudomonas. Actinobacteria strains were found predominantly. Phylogenetic analysis revealed 13 Actinobacteria clusters of Streptomyces, the main genus. Three Streptomycetes, strains MW562814, MW562805, and MW562807 showed antiproliferative activities against three tumor cell lines: U251 glioma, MCF7 breast, and NCI-H460 lung (non-small cell type); and antibacterial activity against Staphylococcus aureus ATCC 6538, Escherichia coli ATCC 10536, and the multidrug resistant Acinetobacter baumannii AC-972. The antiproliferative activities (measured as total growth inhibition [TGI]) of Streptomyces sp. MW562807 were 0.57 μg/mL, for 0.61 μg/mL, and 0.80 μg/mL for glioma, lung non-small cell type, and breast cancer cell lines, respectively; the methanolic fraction of the crude extract showed a better antiproliferative activity and could inhibit the growth of (U251 (TGI = 38.3 μg/mL), OVCAR-03 (TGI = 62.1 μg/mL), and K562 (TGI = 81.5 μg/mL)) of nine tumor cells types and one nontumor cell type. Extreme enviroments, such as the Morrope and Bayovar Salt saloons are promising sources of new bacteria, whose compounds may be useful for treating various infectious diseases or even some types of cancer. [ABSTRACT FROM AUTHOR]

Background: Despite efforts to stop HIV epidemic in Latin America, new HIV cases continue to increase in the region especially among young MSM (YMSM). This study aims to assess if sociodemographic characteristics are associated with self-reported HIV positive status among YMSM from three Latin American countries.Methods: Cross-sectional web-based survey advertised on dating apps (Grindr and Hornet) and Facebook in Brazil, Mexico and Peru. For this analysis, we included YMSM aged 18-24 years who self-reported their HIV status. We used multivariable logistic regression models for each country separately to verify if sociodemographic characteristics (race, education and income) were associated with HIV self-reported status after adjusting for behavior characteristics (sexual attraction and steady partner).Results: Among 43,687 MSM who initiated the questionnaire, 27,318 (62.5%) reported their HIV status; 7001 (25.6%) of whom were YMSM. Most YMSM (83.4%) reported an HIV test in the past year, and 15.7% reported an HIV positive status in Peru, 8.4% in Mexico and 7.7% in Brazil. In adjusted models, low-income was associated with higher odds of self-reported HIV positive status in Brazil (aOR = 1.33, 95%CI: 1.01-1.75) and Peru (aOR = 1.56, 95%CI: 1.02-2.40), but not in Mexico. Lower education was associated with higher odds of self-reported HIV positive status only in Brazil (aOR = 1.35, 95%CI: 1.05-1.75).Conclusions: In this large, cross-country study, self-reported HIV positive status among YMSM was high. Lower socioeconomic status was associated with higher odds of self-reported HIV positive status in Brazil and Peru. There is an urgent need for HIV prevention interventions targeting YMSM, and efforts to address low-income YMSM are especially needed in Peru and Brazil. [ABSTRACT FROM AUTHOR]

Precipitation in the outer tropical Andes is highly seasonal, exhibits considerable interannual variability, and is vital for regulating freshwater availability, flooding, glacier mass balance, and droughts. The primary driver of interannual variability is El Niño Southern Oscillation (ENSO), with most investigations reporting that the El Niño (La Niña) results in negative (positive) precipitation anomalies across the region. Recent investigations, however, have identified substantial spatiotemporal differences in ENSO‐precipitation relationships. Motivated by the dissimilarity of these findings, this study examines a carefully selected data set (≥ 90% completeness) of ground‐based precipitation observations from 75 high‐elevation (≥ 2,500 m above sea level) meteorological stations in the tropical Andes of southern Peru and Bolivia for the period 1972–2016. Distinct groups of stations and associated variability in precipitation characteristics (e.g., total seasonal precipitation, wet season onset, and wet season length) are identified. Using no spatial constraints, the K‐Means algorithm optimally grouped stations into five easily identifiable groups. The groups farthest from the Amazon basin had significant negative (positive) precipitation anomalies (p <.05) during El Niño (La Niña), aligning with the traditional view of ENSO‐precipitation relationships while groups closest to the Amazon had opposite relationships. Additionally, though studies have reported delays in the wet season, years characterized by El Niño had an earlier wet season onset in all five groups. These findings may aid in improving seasonal climate prediction and managing water resources, and could allow for improved interpretation of tropical Andean ice cores. [ABSTRACT FROM AUTHOR]

Activity pattern studies can help explain the coexistence of competing species. Between 2001 and 2017 we evaluated the activity pattern overlap of jaguar (Panthera onca), puma (Puma concolor), and their main prey, using camera traps at 17 Amazonian sites in the Greater Madidi-Tambopata Landscape. We used the Kernel density estimation to generate species activity patterns and the overlap between both cats. We then calculated the overlap coefficient (Δ) by carrying out 10,000 bootstraps (95%). Both cats were active 24 h a day. The puma has higher nocturnal activity (57%), whilst jaguar activity is split almost equally between night (53%) and day (47%). We did not find temporal segregation between jaguars and pumas, which showed similar activity patterns with a high overlapping coefficient (Δ4 = 0.84; 0.78–0.91). Also, we did not find significant differences between Male and Female activity patterns for both species (X2 = 0.50, gl = 1, P = 0.47). Moreover, both cats had significant overlap with the activity patterns of their main prey. Temporal segregation was not detected in any of our study sites within the Greater Madidi-Tambopata Landscape, suggesting that in this region, these predators employ other mechanisms to avoid competition. [ABSTRACT FROM AUTHOR]

Copyright of Educacao e Pesquisa is the property of Faculdade de Educacao da Universidade de Sao Paulo and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Científica is the property of Revista Cientifica, Universidad Distrital Francisco Jose de Caldas and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This article evaluates the short-term impacts of a fruit fly integrated pest management program in Peru. Exploiting arbitrary variation in the program's intervention borders, we use a geographical regression discontinuity design to identify the program's effects on agricultural outcomes. Pre-treatment balance tests show that producer and farm-level pre-treatment characteristics evolve smoothly at the intervention border. Results indicate that farmers within treated areas improved pest knowledge and are more likely to implement prevention and control practices. Also, they increased fruit production and sales. Our findings are confirmed by placebo tests and are robust to alternative regression discontinuity bandwidths and polynomials. [ABSTRACT FROM AUTHOR]

Copyright of Themis: Revista de Derecho is the property of Themis Asociacion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Educade: Spanish Journal of Accounting, Finance & Management Education / Revista de Educación en Contabilidad, Finanzas y Administración de Empresas is the property of Asociacion Espanola de Contabilidad y Administracion de Empresas and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background: Mycobacterium pinnipedii, a member of the Mycobacterium tuberculosis Complex (MTBC), is capable of infecting several host species, including humans. Recently, ancient DNA from this organism was recovered from pre-Columbian mummies of Peru, sparking debate over the origin and frequency of tuberculosis in the Americas prior to European colonization. Results: We present the first comparative genomic study of this bacterial species, starting from the genome sequencing of two M. pinnipedii isolates (MP1 and MP2) obtained from different organs of a stranded South American sea lion. Our results indicate that MP1 and MP2 differ by 113 SNPs (single nucleotide polymorphisms) and 46 indels, constituting the first report of a mixed-strain infection in a sea lion. SNP annotation analyses indicate that genes of the VapBC family, a toxin-antitoxin system, and genes related to cell wall remodeling are under evolutionary pressure for protein sequence change in these strains. OrthoMCL analysis with seven modern isolates of M. pinnipedii shows that these strains have highly similar proteomes. Gene variations were only marginally associated with hypothetical proteins and PE/PPE (proline-glutamate and proline-proline-glutamate, respectively) gene families. We also detected large deletions in ancient and modern M. pinnipedii strains, including a few occurring only in modern strains, indicating a process of genome reduction occurring over the past one thousand years. Our phylogenomic analyses suggest the existence of two modern clusters of M. pinnipedii associated with geographic location, and possibly host species, and one basal node associated with the ancient M. pinnipedii strains. Previously described MiD3 and MiD4 deletions may have occurred independently, twice, over the evolutionary course of the MTBC. Conclusion: The presence of superinfection (i.e. mixed-strain infection) in this sea lion suggests that M. pinnipedii is highly endemic in this population. Mycobacterium pinnipedii proteomes of the studied isolates showed a high degree of conservation, despite being under genomic decay when compared to M. tuberculosis. This finding indicates that further genomes need to be sequenced and analyzed to increase the chances of finding variably present genes among strains or that M. pinnipedii genome remodeling occurred prior to bacterial speciation. [ABSTRACT FROM AUTHOR]

• We exploit random assignment of freshman college students to small study-groups in the context of a government inclusion program in higher-education in Peru: Beca18. • Individuals assigned to study-groups composed by Beca18 (poor) and non-Beca18 (relatively wealthy) students on average improve their academic performance in weekly/biweekly quizzes. • Low incoming academic ability non-Beca18 students benefit the most. Among Beca18 students the opposite pattern is observed. • Driving mechanisms are related to peers' incoming academic ability and peers' traits related to effort and cooperation. Beca18 is a Peruvian social inclusion program for higher education. It provides full scholarships to economically disadvantaged public high school graduates who have been admitted to eligible universities. We exploit the random assignment of first-year students to small study groups at an elite university in Peru to evaluate how the interactions between relatively wealthy non-Beca18 students, who predominate at this institution, and Beca18 fellows affect early academic outcomes. We find that assignment to mixed study groups, composed of Beca18 and non-Beca18 students, on average improves performance on individual weekly/biweekly quizzes. In the case of Beca18 fellows, the positive effect of mixed-study environments is greater among fellows that possess relatively high academic ability as incoming students (that is, among those with higher pre-college academic ability). Interestingly, the opposite holds for non-Beca18 students. We identify two potential underlying mechanisms behind these results: (i) peers' incoming (pre-college) academic ability and (ii) peer's attitudes towards effort and cooperation. Beca18 students in mixed study groups seem to benefit more from the relatively higher academic ability their non-Beca18 peers possess upon entrance. Non-Beca18 students appear to benefit from experiencing the higher effort and cooperation levels displayed by Beca18 fellows. Our evidence also suggests that some individuals may be adversely affected. These include Beca18 students who are toward the bottom of their socioeconomic group and non-Beca18 students who are at the top of their socioeconomic group in terms of pre-college ability distribution. [ABSTRACT FROM AUTHOR]

In a global context of change and uncertainty, the innovation capacity of organizations is key to their sustained development. The objective of this study is to empirically analyze the relationship between innovation and firm performance of micro, small and medium-sized enterprises (MSMEs) in emerging countries and to study the moderating role of investment and collaboration in these relationships. The least squares structural equation model (PLS-SEM) analyzed a sample of 104 SMEs in the wearing apparel sector in Peru and Colombia. Product Innovation together with Business Process Innovation, explained 47.1 % of organizational performance, 41.0 % of economic performance, 39.5 % of commercial performance and 36.9 % of productive performance. However, Product Innovation was not a significant predictor of productive or organizational performance. The moderating effect of Investment on the relationship between Product Innovation and Business Process Innovation and Firm performance was only significant for organizational and productive performance and with respect to the moderating effect of Collaboration on the relationship between Product innovation and Business Process Innovation and Firm performance, in the quantitative analysis no significant prediction was obtained, supported by the results of the surveys where 62.8 % of the MSMEs never received supported from others actors for the development of innovation activities. The application of the findings of this study can contribute to the validation, updating or implementation of public policies that promote collaboration between actors of the innovation ecosystem, as well as in proposal of investment strategies for the development of innovation in emerging countries. [ABSTRACT FROM AUTHOR]