1. Spontaneous lymphoma associated with Herpesvirus saimiri in owl monkeys.
- Author
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Rabin H, Neubauer RH, Pearson GR, Cicmanec JL, Wallen WC, Loeb WF, and Valerio MG
- Subjects
- Animals, Antigens, Viral analysis, Cytopathogenic Effect, Viral, Guinea Pigs, Herpesvirus 4, Human immunology, Leukemia transmission, Leukemia veterinary, Lymphoma immunology, Lymphoma transmission, Peru, Herpesviridae, Lymphoma veterinary, Monkey Diseases transmission
- Abstract
Two cases of lymphoma and one case of lymphoproliferative disease were found in a group of 7 owl monkeys imported into our colony as a single group. Herpesvirus saimiri (HVS) was isolated from the tumor cells of 1 lymphoma by cocultivation and from kidney cell cultures from the monkey with lymphoproliferative disease. Antibody to HVS was found in serum samples from 2 monkeys positive for HVS but not in the sera from the 4 clinically normal monkeys. Antibody to Epstein-Barr virus-infected cells was also found in the serum from the animal with lymphoma.
- Published
- 1975