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Introduction: Obesity and Type II Diabetes Mellitus are increasing in epidemic proportions worldwide, and both increase the incidence of cardiovascular events. Type II DM has long been recognized as a risk factor for stroke, and its association with all-cause mortality is also widely acknowledged. Aims:To know the relation of Body Mass Index to systemic hypertension, type II diabetes mellitus and dyslipidemia (triglyceride, total cholesterol, HDL cholesterol and LDL cholesterol Materials and Methods: Either in patients or out patients of systemic hypertension, type II diabetes mellitus or dyslipidemia coming to Patna Medical College and Hospital, Patna. During the period April 2021 to October 2022.110 Patients were included in this study Result: In our study also showed that mean Triglyceride in BMI <25 was 128.56, in BMI 25 - 29.9 was 140.08 and in BMI >30was 175.67. Mean TG was increases with the increase of BMI. Mean HDL in BMI <25 was 58.80, in BMI 25 - 29.9 was 52.71 and in BMI >30was 44.17. Mean HDL was decreases with the increase of BMI. Mean LDL in BMI <25 was 107.87, in BMI 25 - 29.9 was 122.00 and in BMI >30was 153.83. Mean LDL was increases with the increase of BMI. Mean Total Cholesterol (TC) in BMI <25 was 186.31, in BMI 25 - 29.9 was 200.53 and in BMI >30was 231.67. Mean TC was increases with the increase of BMI. Conclusion: Present study highlights the implication of BMI in day-to-day clinical practice in detecting the patients with high chronic diseases risk like hypertension, diabetes, and dyslipidaemia. [ABSTRACT FROM AUTHOR]