1. The prognostic significance of urinary albumin in Polynesians with non-insulin-dependent diabetes.
- Author
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Lunt H, Graham PJ, Jury DR, Lim CW, Crooke MJ, Smith RB, and Dunn PJ
- Subjects
- Diabetes Mellitus, Type 2 mortality, Diabetic Nephropathies epidemiology, Diabetic Nephropathies mortality, Diabetic Nephropathies therapy, Female, Follow-Up Studies, Humans, Male, Middle Aged, New Zealand, Pacific Islands ethnology, Predictive Value of Tests, Prognosis, Proportional Hazards Models, Registries, Renal Dialysis, White People, Albuminuria, Diabetes Mellitus, Type 2 urine
- Abstract
Polynesian (59 Maori and 30 Pacific Island) patients were identified from two diabetes clinic registers and followed for a mean of 4.8 years, in order to determine the prognostic significance of urinary albumin excretion. Events were defined as death or entry onto a renal replacement programme. Fourteen events occurred during the period of follow-up. Urinary albumin/creatinine ratio was treated as a continuous variable in a proportional hazards analysis. A 10-fold increase in albumin/creatinine ratio was associated with a 5-fold increase in the risk of an event (95% C.I. = 2.05-12.09). In conclusion, elevated urinary albumin/creatinine predicted mortality and renal morbidity in Maori and Pacific Island patients with non-insulin-dependent diabetes.
- Published
- 1994
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