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Pediatric inflammatory bowel disease (PIBD) is rising rapidly in many industrialized and affluent areas in the Asia‐Pacific region. Current available guidelines, mainly from Europe and North America, may not be completely applicable to clinicians caring for children with PIBD in this region due to differences in disease characteristics and regional resources constraints. This position paper is an initiative from the Asian Pan‐Pacific Society for Pediatric Gastroenterology, Hepatology and Nutrition (APPSPGHAN) with the aim of providing an up‐to‐date, evidence‐based approach to PIBD in the Asia‐Pacific region, taking into consideration the unique disease characteristics and financial resources available in this region. A group of pediatric gastroenterologists with special interest in PIBD performed an extensive literature search covering epidemiology, disease characteristics and natural history, management, and monitoring. Gastrointestinal infections, including tuberculosis, need to be excluded before diagnosing IBD. In some populations in Asia, the Nudix Hydrolase 15 (NUD15) gene is a better predictor of leukopenia induced by azathioprine than thiopurine‐S‐methyltransferase (TPMT). The main considerations in the use of biologics in the Asia‐Pacific region are high cost, ease of access, and potential infectious risk, especially tuberculosis. This position paper provides a useful guide to clinicians in the medical management of children with PIBD in the Asia‐Pacific region. [ABSTRACT FROM AUTHOR]

The article presents the 2017 Asia-Pacific Working Party on Non-Alcoholic Fatty Liver Disease guidelines which cover disease management and special groups. It cites several ways to manage the disease which include diet and exercise programs and dietary considerations. Information is also presented on pharmacological treatments, such as the use of statins. The management of the disease in children and adolescents is also discussed.

The article presents the 2017 Asia-Pacific Working Party on Non-Alcoholic Fatty Liver Disease guidelines which cover diagnosis, screening, assessment and treatment. It discusses a proposed positive definition of the disease which is related to over-nutrition in the absence of excessive alcohol consumption. It also offers information on the pathological subtypes and outcomes of the disease.