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The goal of this retrospective study was to determine the benefit in using abdominal compression to reduce tumor motion for patients treated with lung stereotactic body radiotherapy. Forty-four lung lesions (n = 44) from 37 patients (N = 37) treated at the University of Toledo's Dana Cancer Center were assessed by determining the overall tumor displacement along with possible surrogates such as change in tidal volume and diaphragm displacement, with and without abdominal compression. Measurements of lung capacity were acquired from the 4DCT at maximum and minimum respiration in order to determine the tidal volume, with and without abdominal compression. Tumor centroid and diaphragm apex motion was then assessed in 3 dimensions from phase 0 to phase 50. This was measured in centimeters using the ruler method on MIM software, both with and without the compression belt. Change in overall tumor movement was 0.61 cm ± 0.09 cm with compression, and 0.60 cm ± 0.09 cm without the compression belt. Delta tumor motion was reduced in 5 cases, increased (made worse) in 6 cases, and did not clinically impact the remaining 33 cases. Average tidal volume with abdominal compression was 379.7 mL or 12.0% ± 0.724% of total lung volume while average tidal volume without abdominal compression was 337.7 mL or 10.5% ± 0.649% of total lung volume. Change in diaphragm position throughout the breathing cycle was 1.21 cm ± 0.10 cm with compression, and 1.28 ± 0.13 cm without the compression belt. These findings indicate that abdominal compression may not be an effective method in the reduction of respiratory motion, and can even negatively impact tumor motion by increasing its displacement. Compression decreased tumor motion in 5 out of the 44 cases studied. The 5 cases that benefitted tended to be lesions close to the diaphragm but these 5 corresponded to less than half of the inferior lesions, suggesting that even inferior lung lesions may not be prime candidates for abdominal compression., (Copyright © 2019 American Association of Medical Dosimetrists. Published by Elsevier Inc. All rights reserved.)