1. Octreotide in children with hypoglycaemia due to sulfonylurea ingestion.
- Author
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Rath S, Bar-Zeev N, Anderson K, Fahy R, and Roseby R
- Subjects
- Child, Preschool, Female, Glucagon administration & dosage, Glucose administration & dosage, Glyburide poisoning, Humans, Hypoglycemia drug therapy, Infant, Infusions, Intravenous, Male, Northern Territory, Hypoglycemia chemically induced, Hypoglycemic Agents poisoning, Octreotide administration & dosage, Sulfonylurea Compounds poisoning
- Abstract
Sulfonylureas are commonly prescribed for type 2 diabetes mellitus; however, overdose or accidental ingestion may result in profound and prolonged hypoglycaemia with permanent neurological sequelae and death. We describe two cases of children with hypoglycaemia due to presumed accidental ingestion of sulfonylureas, where traditional methods of raising blood sugar levels were unsatisfactory. Two studies describe Octreotide for adults with hypoglycaemia, but there are no studies examining the use of Octreotide in children for this indication. Given that Octreotide has been shown to be safe in children when used for other indications, we used Octreotide to safely restore euglycaemia.
- Published
- 2008
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