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1. Frequency of cytokine gene promoter polymorphisms in the Northern Ireland cystic fibrosis population.

Author

Watt AP, Ross OA, Courtney J, Middleton D, Ennis M, and Elborn JS

Subjects
Adult, Cystic Fibrosis epidemiology, Female, Gene Frequency, Humans, Male, Middle Aged, Northern Ireland epidemiology, Cystic Fibrosis genetics, Cytokines genetics, Polymorphism, Genetic, Promoter Regions, Genetic genetics
Abstract

It has been postulated that cytokine allele frequencies are gender and perhaps geographically-specific. Cytokine release is crucial in the regulation of the type and magnitude of the immune response. This study observed no differences in the frequency of cytokine promoter polymorphisms associated with variant levels of expression in patients with CF and a non-CF population of Northern Ireland.

Published
2007
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