1. Haemoglobin F and A2 in Nigerian children with sickle cell anaemia.
- Author
-
Fatunde OJ and Scott-Emuakpor AB
- Subjects
- Adolescent, Anemia, Sickle Cell diagnosis, Child, Child, Preschool, Female, Humans, Infant, Male, Nigeria, Anemia, Sickle Cell blood, Fetal Hemoglobin physiology, Hemoglobin A2 physiology
- Abstract
The concentration of haemoglobins F and A2 in 132 Hb SS children aged 6 months to 16 years and 50 age- and sex-matched controls has been determined. The mean HbF concentration in Hb SS patients and controls were 9.5 per cent (range 1.7-24.5 per cent) and 1.5 per cent (range 0.5-14.4 per cent) respectively while HbA2 concentrations were 2.7 per cent (range 1.6-3.7 per cent) and 2.4 per cent (range 1.3-3.9 per cent) respectively. For 18 Hb SS patients seen in the stable state and during vaso-occlusive crisis, there was no significant difference in HbF concentration between the two states.
- Published
- 1993
- Full Text
- View/download PDF