1. A population-based study of visual inspection with acetic acid (VIA) for cervical screening in rural Nigeria.
- Author
-
Ajenifuja KO, Gage JC, Adepiti AC, Wentzensen N, Eklund C, Reilly M, Hutchinson M, Burk RD, and Schiffman M
- Subjects
- Adenocarcinoma epidemiology, Adenocarcinoma virology, Adolescent, Adult, Aged, Aged, 80 and over, Carcinoma, Squamous Cell epidemiology, Carcinoma, Squamous Cell virology, Early Detection of Cancer, Female, Follow-Up Studies, Humans, Middle Aged, Neoplasm Staging, Nigeria epidemiology, Papillomaviridae genetics, Papillomavirus Infections epidemiology, Papillomavirus Infections virology, Prevalence, Prognosis, Risk Factors, Rural Population, Uterine Cervical Neoplasms epidemiology, Uterine Cervical Neoplasms virology, Young Adult, Uterine Cervical Dysplasia epidemiology, Uterine Cervical Dysplasia virology, Acetic Acid, Adenocarcinoma diagnosis, Carcinoma, Squamous Cell diagnosis, Mass Screening, Papillomavirus Infections diagnosis, Uterine Cervical Neoplasms diagnosis, Uterine Cervical Dysplasia diagnosis
- Abstract
Objective: Cervical cancer is the most common gynecological cancer in developing countries. Visual inspection with acetic acid (VIA) was introduced to screen for cervical premalignant lesions in developing countries owing to the inability of many countries to implement high-quality cytologic services. We sought to compare VIA performance among different health workers in Nigeria., Methods: In a population-based project, 7 health workers who had been screening women with VIA for approximately 2 years at local government health centers in rural Nigeria were retrained in a 2-week program using the International Agency for Research on Cancer training manual. Women from a rural village who had never had cervical cancer screening were recruited into the study. Each woman had cervical cancer screening by VIA, liquid-based cytologic test, and oncogenic human papillomavirus (HPV) DNA test., Results: Despite similar participant characteristics, across all age groups, providers had wide ranges of VIA results; 0% to 21% suspect cancer and 0% to 25% were VIA positive. Visual inspection with acetic acid was insensitive compared to a combination of cytologic and HPV tests., Conclusion: In our study, VIA was not reproducible, nor was it sensitive compared to cytologic and HPV tests.
- Published
- 2013
- Full Text
- View/download PDF