Search

Your search keyword '"Miller, J. H."' showing total 1 results
Start Over Author "Miller, J. H." Region new zealand

Refine your results

1 results on '"Miller, J. H."'

1. Mycalamide D, a new cytotoxic amide from the New Zealand marine sponge Mycale species.

Author

West LM, Northcote PT, Hood KA, Miller JH, and Page MJ

Subjects
Animals, Antineoplastic Agents pharmacology, Drug Screening Assays, Antitumor, Humans, LLC-PK1 Cells, Magnetic Resonance Spectroscopy, Mass Spectrometry, Molecular Conformation, New Zealand, Pyrans pharmacology, Spectrophotometry, Ultraviolet, Stereoisomerism, Swine, Tumor Cells, Cultured, Antineoplastic Agents isolation & purification, Porifera chemistry, Pyrans isolation & purification
Abstract

A new mycalamide, mycalamide D (3), has been isolated from the New Zealand marine sponge Mycale sp. This new metabolite, in which the C13-O-methyl group of mycalamide A (1) is replaced by a hydrogen atom, was found to be cytotoxic to a range of mammalian cell lines, with a potency approximately 20-fold less than that of 1.

Published
2000
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results