1. Meningococcal disease in the United States--1986. Meningococcal Disease Study Group.
- Author
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Pinner RW, Gellin BG, Bibb WF, Baker CN, Weaver R, Hunter SB, Waterman SH, Mocca LF, Frasch CE, and Broome CV
- Subjects
- Adolescent, Adult, Anti-Bacterial Agents pharmacology, Child, Child, Preschool, Humans, Incidence, Infant, Infant, Newborn, Los Angeles epidemiology, Middle Aged, Missouri epidemiology, Neisseria meningitidis classification, Neisseria meningitidis drug effects, Neisseria meningitidis immunology, New Jersey epidemiology, Oklahoma epidemiology, Population Surveillance, Seasons, Serotyping, Tennessee epidemiology, United States epidemiology, Washington epidemiology, Meningococcal Infections epidemiology
- Abstract
Active surveillance for invasive meningococcal disease was conducted during 1986 and 1987 in six areas of the United States with a total population of approximately 34 million persons. The incidence of meningococcal disease was 1.3:10(5). The highest incidence of disease among the surveillance areas was in Los Angeles County (1.65:10(5). Neisseria meningitidis serogroups B and C caused about equal amounts of disease, which reflects a recent increase in the incidence of group C disease. Group C caused more than half of the cases of meningococcal disease in Los Angeles and Tennessee but less than one-third of the cases in Missouri and Oklahoma. Multilocus enzyme electrophoresis demonstrated that a group of closely related isolates of N. meningitidis was prevalent in Los Angeles during the surveillance period and was associated with an increased incidence of meningococcal disease there.
- Published
- 1991
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