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The purpose of nutrition screening is to identify individuals at high nutritional risk. Given that dietitians cannot always carry out screening in health-care facilities, tools should be simple and based on data obtained from the nursing admission questionnaire. This study was conducted to develop timely and valid tools for screening protein-energy malnutrition (PEM). A dietetic technician administered an initial screening tool to 160 subjects recruited from two settings. This tool comprised nine PEM risk factors. The sample included 54 adults in acute care, 57 elderly adults in acute care, and 49 elderly adults in long-term care. Dietitians performed comprehensive nutritional assessments to determine the validity of this screening tool. Stepwise regression analysis revealed significant risk factors among those included in the initial screening. These risk factors were considered during development of the first simple screening tool, which encompassed body mass index (BMI) and percentage of weight loss, and classified subjects as having low or high PEM risk levels. A second tool using BMI and albumin level was tested in cases where an albumin measurement was available upon admission. These simple tools had validity indices of 75.9% or higher, except in adults in acute care; sensitivity was low in this group. The tools proved helpful in establishing dietitians' priorities for involvement and in initiating early nutritional care.