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This article discusses the circulation of information extracted from François Valentyn's Oud en Nieuw Oost-Indiën (1724-1726) during the eighteenth century, both with regards to the central organs of the Dutch East India Company (VOC) in the Netherlands and the VOC establishments in the East Indies. First, three documents are analysed that were part of five VOC directors' personal archives, with the aim to determine the way these directors made use of Valentyn's book. It is concluded that for these directors Oud en Nieuw Oost-Indiën was probably the most important source of information about the VOC's trading empire, while at the same time their epistemic interest was limited to matters of trade. Second, the usage of Valentyn's book in various VOC establishments in the East Indies is assessed on the basis of correspondence between these establishments with the VOC central government in Batavia. Because of the fact that Oud en Nieuw Oost-Indiën was used simultaneously as a source of information by several actors, both in the Netherlands and in the East Indies, this might have resulted in standardising the operational knowledge of the East Indies within the VOC network. [ABSTRACT FROM AUTHOR]

Aims: Left bundle branch block (LBBB) is induced in approximately one-third of all transcatheter aortic valve implantation (TAVI) procedures. We investigated electrophysiological remodelling in patients with TAVI-induced LBBB.Methods and Results: This retrospective study comprises 107 patients with initially narrow QRS complex of whom 40 did not and 67 did develop persistent LBBB after TAVI. 12-lead electrocardiograms (ECGs) taken before TAVI, within 24 hours ('acute'), and 1-12 months after TAVI ('chronic') were used to reconstruct vectorcardiograms. From these vectorcardiograms, QRS and T-wave area were calculated as comprehensive indices of depolarization and repolarization abnormalities, respectively. TAVI-induced LBBB resulted in significant acute depolarization and repolarization changes while further repolarization changes were observed with longer lasting LBBB. The amount of long-term repolarization changes (remodelling) was highly variable between patients. The change in T-wave area between acute and chronic LBBB ranged from +57% to - 77%. After dividing the LBBB cohort into tertiles based on the change in T-wave area, only baseline QRS area was larger in the tertile with no significant change in T-wave area. During longer lasting LBBB, the spatial vector gradient (SVG) changed orientation towards the direction of the QRS-vector, indicating that later-activated regions developed shorter action potential duration.Conclusion: This study in patients with TAVI-induced LBBB shows that repolarization changes develop within months after onset of LBBB, and that these changes are highly variable between individual patients. [ABSTRACT FROM AUTHOR]