1. Comparative study of preceding Campylobacter jejuni infection in Guillain-Barré syndrome in Japan and The Netherlands.
- Author
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Koga, M, Ang, C W, Yuki, N, Jacobs, B C, Herbrink, P, van der Meché, F G, Hirata, K, and van Doorn, P A
- Subjects
CAMPYLOBACTER ,CAMPYLOBACTER infections ,COMPARATIVE studies ,ENZYME-linked immunosorbent assay ,RESEARCH methodology ,MEDICAL cooperation ,GUILLAIN-Barre syndrome ,RESEARCH ,EVALUATION research - Abstract
A comparative study was made in Japan and The Netherlands of the presence of preceding Campylobacter jejuni infections in Guillain-Barré syndrome (GBS). It was conducted in two laboratories using different serological criteria. The Japanese results showed no significant difference in the frequency of C jejuni infection between the Japanese (17/88, 19%) and Dutch (21/132, 16%) patients with GBS. The Dutch investigation showed a higher frequency in Dutch patients (45/132; 34%) than in Japanese patients(20/88; 23%), but the difference did not reach significance. Although the frequencies of preceding C jejuni infection have been reported to be higher in Asian countries than in western countries, the findings of this collaborative study show that the incidence of antecedent C jejuni infection in GBS in Japan is not higher than in The Netherlands and that serological assays vary considerably between laboratories. [ABSTRACT FROM AUTHOR]
- Published
- 2001