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Your search keyword '"Histone deacetylases"' showing total 2 results
Start Over Descriptor "Histone deacetylases" Region nanjing (jiangsu sheng, china)
2 results on '"Histone deacetylases"'

1. New Solid Cancer Study Findings Recently Were Reported by Researchers at China Pharmaceutical University [Exploration of Janus Kinase (Jak) and Histone Deacetylase (Hdac) Bispecific Inhibitors Based On the Moiety of Fedratinib for Treatment of...].

Subjects
MOIETIES (Chemistry), PROTEIN-tyrosine kinases, JANUS kinases, NUCLEOPROTEINS, AMIDASES, HISTONE deacetylase
Abstract

For more information on this research see: Exploration of Janus Kinase (Jak) and Histone Deacetylase (Hdac) Bispecific Inhibitors Based On the Moiety of Fedratinib for Treatment of Both Hematologic Malignancies and Solid Cancers. Keywords: Nanjing; People's Republic of China; Asia; Amidohydrolases; Cancer; Deacetylase; Enzymes and Coenzymes; Health and Medicine; Histone Deacetylases; Histones; Intracellular Signaling Peptides and Proteins; Janus Kinases; Kinase; Nucleoproteins; Oncology; Phosphotransferases; Protein-Tyrosine Kinases; Proteins; Solid Cancer EN Nanjing People's Republic of China Asia Amidohydrolases Cancer Deacetylase Enzymes and Coenzymes Health and Medicine Histone Deacetylases Histones Intracellular Signaling Peptides and Proteins Janus Kinases Kinase Nucleoproteins Oncology Phosphotransferases Protein-Tyrosine Kinases Proteins Solid Cancer 568 568 1 05/22/23 20230523 NES 230523 2023 MAY 23 (NewsRx) -- By a News Reporter-Staff News Editor at Cancer Weekly -- Investigators discuss new findings in Oncology - Solid Cancer. [Extracted from the article]

Published
2023

2. New Apoptosis Data Have Been Reported by Researchers at Nanjing Normal University (Switching the Mode of Cell Death Between Apoptosis and Autophagy By Histone Deacetylase 6 Inhibition Levels).

Subjects
CELL death, APOPTOSIS, HISTONE deacetylase, AUTOPHAGY, TUMOR proteins, NUCLEOPROTEINS
Abstract

The anticancer mechanism of Ir-VPA to HeLa cells was dependent on the HDAC6 inhibitory performance, as the caspase dependent apoptosis at low concentration (IC50) and autophagy with the autophagy flux blockage at high concentration (2xIC(50)). Keywords: Nanjing; People's Republic of China; Asia; Amidohydrolases; Anticancer Agents; Apoptosis; Cancer; Cancer Therapy; Cellular Physiology; Deacetylase; Drugs and Therapies; Enzymes and Coenzymes; Health and Medicine; Hela Cells; Histone Deacetylases; Histones; Nucleoproteins; Oncology; Pharmaceuticals; Protective Agents; Proteins; Tumor Cell Line EN Nanjing People's Republic of China Asia Amidohydrolases Anticancer Agents Apoptosis Cancer Cancer Therapy Cellular Physiology Deacetylase Drugs and Therapies Enzymes and Coenzymes Health and Medicine Hela Cells Histone Deacetylases Histones Nucleoproteins Oncology Pharmaceuticals Protective Agents Proteins Tumor Cell Line 353 353 1 03/24/23 20230224 NES 230224 2023 FEB 21 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Fresh data on Cellular Physiology - Apoptosis are presented in a new report. [Extracted from the article]

Published
2023

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