1. [Hemoglobinopathies in students at the Russian University of the Friendship of Peoples].
- Author
-
Troitskaia OV, Kuznetsov VI, and Iushkova NM
- Subjects
- Adult, Africa ethnology, Diagnosis, Differential, Female, Hemoglobinopathies blood, Hemoglobinopathies diagnosis, Hemoglobinopathies genetics, Humans, Infant, Male, Moscow epidemiology, Pedigree, Prevalence, Hemoglobinopathies ethnology, Students statistics & numerical data
- Abstract
Screening of the university students for hemoglobinopathies detected 153 patients with various hemoglobin abnormalities; 69 with Hb AS, 3 with Hb S-beta-thalassemia, 4 with Hb S-alpha-thalassemia, 3 with hb SC, 1 with Hb SK, 1 with Hb CC, 38 with Hb AC, 1 with Hb A O Arab, 4 with Hb EE, 25 with Hb AE, 1 with Hb AD, 1 with Hb AI, 1 with beta-thalassemia major, and 1 with beta-thalassemia minor. The most grave disease was observed in a child with Hb S-beta-thalassemia and in a youth with beta-thalassemia major. The patterns of Hb SC disease varied. The majority of heterozygote carriers of Hb S, Hb C, Hb E, etc. were healthy. A total of 7000 students were screened by express electrophoresis on cellulose acetate films. more than 400 subjects with abnormal hemoglobins were detected, the most numerous of which were heterozygote carriers of Hb S (Hb AS).
- Published
- 1999