Lozano-Sardaneta, Yokomi N., Rodríguez-Rojas, Jorge J., Huerta, Herón, Benítez-Alva, José Ismael, Santander-Gómez, Alberto Andres, Luna-Luna, Alba Magali, Cervantes, Cristian, Correa-Morales, Fabián, and Contreras-Ramos, Atilano
• Geographical distribution of 22 sand fly species in leishmaniasis endemic areas of Mexico is updated, as well as altitudinal and bioclimatic patterns of their distribution are identified. • We recorded sand fly species for the first time in the states of Morelos (3); Oaxaca (7) and Tabasco (1), Mexico. • The 82 % of sand fly specimens collected are distributed in areas with altitudinal ranges between 1 and 540 m.a.s.l. • In a PCA of Worldclim variables, 72 % of variation of sand fly species distribution is correlated with temperature of coldest month and precipitation of wettest quarter. • Sand fly species Psathyromyia shannoni, Psathyromyia carpenteri, Lutzomyia cruciata , and Lutzomyia longipalpis displayed the greatest variability regarding altitudinal ranges and climatic variables. This study updates knowledge on historical geographic distribution of sand fly species through identifying altitudinal and bioclimatic patterns in leishmaniasis endemic areas in Mexico. We analyze and identify sand fly specimens obtained through national efforts by the Instituto de Diagnóstico y Referencia Epidemiológicos (InDRE, Mexico), collected between 1995 and 2001, 2008–2012, and 2017–2023, and add bibliographic information (427 additional records). After a principal components analysis of WorldClim variables and altitudinal ranges, variables that better explain the distribution of sand fly species were chosen (BIO6, BIO12, and BIO16, explaining 72 % of variation). A total of 1,187 specimens of 22 species were retrieved from eight states, providing 29 new municipalities and 48 new localities, being Lutzomyia cruciata, Micropygomyia chiapanensis , and Psathyromyia shannoni the most common species. We presented new historical records of distribution for sand fly species from Morelos (3), Oaxaca (7) and Tabasco (1). The 82.7 % of sand fly species analyzed were distributed in areas with altitudinal ranges below 420 m. The anthropophilic species Psathyromyia shannoni , and Lutzomyia cruciata showed the greatest variability regarding altitudinal range, and climatic preferences, while several wild species showed abiotic preferences. It is likely that the effect of urbanization and climate change generate new beneficial biotopes for the proliferation of the vector sand fly species. Complementary studies that consider seasonality, vegetation types, and change in land use could provide new information to better understand the spread of vector-borne diseases. This is the first country-level effort to update knowledge on geographical distribution of sand fly species in leishmaniasis endemic areas in Mexico, as well as to identify altitudinal and bioclimatic patterns of their distribution. [Display omitted] [ABSTRACT FROM AUTHOR]