1. Management experience of pediatric meningioma in a Mexican reference center.
- Author
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Santana-González A, Pérez-Ramírez M, Ramírez-Reyes G, Sánchez-Rodríguez G, Ferman-Cano F, López-Aguilar E, and Siordia-Reyes AG
- Subjects
- Adolescent, Child, Child, Preschool, Female, Humans, Male, Meningeal Neoplasms diagnosis, Meningeal Neoplasms epidemiology, Meningeal Neoplasms pathology, Mexico epidemiology, Neoplasm Grading, Prevalence, Retrospective Studies, Young Adult, Meningioma diagnosis, Meningioma epidemiology, Meningioma pathology
- Abstract
Objective: Determine the histopathological and clinical characteristics of patients diagnosed with meningiomas and to establish the frequency of these tumors in the pediatric population Mexican. Determine the NF1/2 frequency in meningioma pediatric., Methods: Samples from the histopathology file were reviewed, and from the complete clinical file the following patient data was reviewed: age, gender, diagnosis, diagnosis year, surgical resection, location, tumor size, symptoms, and family background. The frequency of NF1/2 in pediatric meningioma was reviewed in literature., Results: Forty-four de novo cases were collected from pediatric patients; 19 were female patients and 25 males. The most frequent histological subtype was transitional meningioma. Of all the cases, 75% had a supratentorial localization and 20% had an extramedullary intrarachidian localization. Some clinical manifestations included seizures, paresis, headache, and visual disturbances., Conclusion: There is a low incidence of meningiomas in the pediatric population, more than 70% are Grade I, and they have supratentorial localization., (Copyright © 2021 Elsevier Inc. All rights reserved.)
- Published
- 2021
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