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La obesidad es actualmente un problema de salud pública de ámbito internacional. Es considerada como la segunda causa de muerte prevenible en México, después del tabaquismo, según la Organización Mundial de la Salud. Actualmente, las opciones quirúrgicas son la gastrectomía en manga, el bypass gástrico o derivación gástrica, la banda gástrica y el bypass gástrico en omega, cada una con sus indicaciones. Se presenta el caso clínico de una paciente con intususcepción yeyuno-yeyunal secundaria a bypass gástrico en el embarazo., Obesity is currently an international public health problem. It is considered the second preventable cause of death in Mexico, after smoking, according to the World Health Organization. Currently, surgical options are sleeve gastrectomy, gastric bypass or gastric derivation, gastric banding, and omega gastric bypass, each with specific indications. The objective of the article is to present the clinical case of a patient with jejuno-jejunal intussusception secondary to gastric bypass in pregnancy., (Copyright: © 2020 Permanyer.)

Obesity prevalence has increased in the last decades worldwide leading to metabolic complications, such as type 2 diabetes, steatosis, cardiovascular disease, among others; its development is influenced by genetic factors and environmental factors, such as intestinal microbiome. In Mexico, 33.3% of the adults present this disease. Obesity is defined as an excessive adipose tissue accumulation, provoking its dysfunction. Adipose tissue remodeling, which involves angiogenesis, hypoxia and inflammation, is implicated in the developing of obesity and metabolic modifications. Bariatric surgery is the most used and successful intervention to control morbid obesity, leading a maintained loss of weight and remission of some of its comorbidities as type 2 diabetes. Here, we review some of the molecular aspects of the metabolic changes provoked by bariatric surgery and its impact in weight loss and comorbidities remission. In summary, this article reviews the genetic aspects, microbiome and molecular facts (adipose tissue remodeling) that are involved in obesity development. In addition, some of the molecular aspects about bariatric surgery are described and the mechanisms that are regulated to control obesity and its comorbidities., (Copyright: © 2019 Permanyer.)