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Ingavirin was shown to be efficient in inhibition of the influenza virus strains A/California/04/2009 and A/California/07/2009 (H1N1) in the MDCK cell culture. The coefficient of the cytopathic activity inhibition amounted to 50 and 60%, and the inhibition coefficients of the specific hemagglutinin formation were 50 and 50%, and 79,1 and 75% before and after the enrichment in chick embryos respectively.

The bioactive amides affinin and capsaicin isolated respectively from Heliopsis longipes roots and Capsicum spp fruits, were assayed for activity against Escherichia coli, Pseudomonas solanacearum, Bacillus subtilis and Saccharomyces cerevisicae suspension cultures. The alkamide affinin inhibited growth of E. coli and S. cerevisiae at concentrations as low as 25 microg/ml. Higher concentrations of affinin were necessary to inhibit growth of P. solanacearum and B. subtilis. However. high concentrations of capsaicin only retarded the growth of E. coli and P. solanacearum, whereas growth of B. subtilis was strongly inhibited and that of S. cerevisiae was initially enhanced. Results are discussed in relation to previous reports concerning crude extract and to the molecular structures of the bioactive compounds.