1. [Changing aspects of cirrhotic disease in a hepato-gastroenterology service in Mali].
- Author
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Diarra M, Konaté A, Soukho A, Dicko M, Kallé A, Doumbia K, Sow H, Traoré HA, and Maiga MY
- Subjects
- Adult, Ascites epidemiology, Ascites etiology, Carcinoma, Hepatocellular etiology, Carcinoma, Hepatocellular mortality, Cholestasis, Intrahepatic epidemiology, Cholestasis, Intrahepatic etiology, Female, Follow-Up Studies, Gastrointestinal Hemorrhage etiology, Gastrointestinal Hemorrhage mortality, Global Health, Hepatic Encephalopathy etiology, Hepatic Encephalopathy mortality, Humans, Liver Neoplasms etiology, Liver Neoplasms mortality, Male, Mali epidemiology, Middle Aged, Morbidity trends, Prevalence, Risk Factors, Young Adult, Liver Cirrhosis epidemiology
- Abstract
The main goal of our study was to evaluate cirrhosis course on one year. The study was prospective and longitudinal from January 2005 to December 2006 in the center of hepatology and gastro-enterology of CHU Gabriel Touré. The patients had one year follow up and examinated every three months. In this study 57 patients were included. Mean age was 41,5 + 15,3 years. Ascite and jaundice were the main clinical signs respectively 70.2% and 54.4%. Ascite or its increase was the most complication in 67.5% of cases (p = 0.002). The global mortality was 82.5% and it was high in the three first months, caused by hepatocellular carcinoma, digestive bleeding and hepatic encephalopathy respectively 33.3%, 27.3% and 15.2%. Abdomen pain, ascite and jaundice have an predictive value for high mortality (p between 3.10-3 et 10-7). Early examination, therapeutic observance and good management of cirrhosis complications could reduce the mortality.
- Published
- 2010