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This research intends to investigate factors affecting students' behavioural intentions to use a massive open online courses (MOOCs) system. Integrating the technology acceptance model (TAM) with the innovation diffusion theory (IDT), the present research proposes an extended technology acceptance model. Testing of data collected from 1148 students using (MOOCs) system in Malaysia achieved the research objective. The findings obtained via a quantitative research method, based on analysing the results using a Structure Equation Modeling (SEM). The outcomes reveal that six views of novelty features swayed students' a (MOOCs) scheme behavioural objective. The properties of the relative advantages, intricacy, trialability, observability, compatibility, and perceived enjoyment on the perceived ease of use are significant. Also, the effects of the relative advantages, complexity, trialability, observability, compatibility, and perceived enjoyment on the usefulness have a substantial impact. Therefore, the practical outcomes offer robust backing for the integrative method between TAM and IDT. The results recommend a prolonged model of TAM with IDT for the taking of MOOCs) system used to improve students learning performance, which can help decision makers in higher education, universities and colleges to planning, evaluating and executing the use of (MOOCs) systems.

The study investigates the influence of tractor forward speeds in predicting the reasonableness of the hypothesis on depth of mulching of oil palm fronds. In the oil palm industry, only 10% palm oil is produced and the remaining in the form of wastes, estimated at 80 million dry tonnes annually in Malaysia. To mulch this amount of wastes to the required depth, an optimum tractor forward speed is needed. Four blades with different lifting angles, two tractor PTO speeds and three tractor forward speeds were assessed using parametric test at Universiti Putra Malaysia oil palm plantation. The result shows that the best-fit regression equation was a quadratic regression with high coefficient of determination. It indicates that change on tractor forward speeds interaction has significant effect using Tukey’s Studentized mean comparison when predicting the depth of mulching. Ninety-seven percent of the depth of mulching variance is explained by three factors interaction. Since tractor forward speed was a major predictor of depth of mulching, the implication of this result is that change in tractor forward speeds predicts the depth of mulching in an oil palm plantation significantly. Additionally, the predicted model can further be used to predict depth of mulching during field operation, replanting and access operation for mulching of oil palm fronds. Conclusively, blades with 120o gave the best mulching depth and a tractor forward speed of 0.57 km h-1 as the recommended speed. [ABSTRACT FROM AUTHOR]

Malaysia reported the first human case of Nipah virus (NiV) in late September 1998 with encephalitis and respiratory symptoms. As a result of viral genomic mutations, two main strains (NiV-Malaysia and NiV-Bangladesh) have spread around the world. There are no licensed molecular therapeutics available for this biosafety level 4 pathogen. NiV attachment glycoprotein plays a critical role in viral transmission through its human receptors (Ephrin-B2 and Ephrin-B3), so identifying small molecules that can be repurposed to inhibit them is crucial to developing anti-NiV drugs. Consequently, in this study annealing simulations, pharmacophore modeling, molecular docking, and molecular dynamics were used to evaluate seven potential drugs (Pemirolast, Nitrofurantoin, Isoniazid Pyruvate, Eriodictyol, Cepharanthine, Ergoloid, and Hypericin) against NiV-G, Ephrin-B2, and Ephrin-B3 receptors. Based on the annealing analysis, Pemirolast for efnb2 protein and Isoniazid Pyruvate for efnb3 receptor were repurposed as the most promising small molecule candidates. Furthermore, Hypericin and Cepharanthine, with notable interaction values, are the top Glycoprotein inhibitors in Malaysia and Bangladesh strains, respectively. In addition, docking calculations revealed that their binding affinity scores are related to efnb2-pem (- 7.1 kcal/mol), efnb3-iso (- 5.8 kcal/mol), gm-hyp (- 9.6 kcal/mol), gb-ceph (- 9.2 kcal/mol). Finally, our computational research minimizes the time-consuming aspects and provides options for dealing with any new variants of Nipah virus that might emerge in the future., (© 2023. This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.)

Studies exploring excessive Internet use and gambling are rapidly expanding concerns regarding its impact on mental health, especially in young people due to the increased prevalence of Internet and gambling addictions. Research suggests that perceived peer support plays a significant role in adolescents' psychological well-being. However, no empirical study has dealt with the mediating effect of perceived peer support on the relationship between Internet and gambling addictions and psychological well-being. Thus, the present study aimed to examine whether perceived peer support mediates the relation between Internet and gambling addictions and psychological well-being of adolescents. A sample of 347 Iranian adolescents aged 14 to 18 (Mean age 16.14, 50.4% male) who were studying in Kuala Lumpur, Malaysia participated in this study. Subjective Vitality Scale (SVS), Compulsive Internet Use Scale (CIUS), Six-item Social Support Questionnaire (SSQ6), and The South Oaks Gambling Screen (SOGS) were used to collect data. Mediation analyses showed a significant indirect effect of compulsive Internet use and problem gambling on psychological well-being through perceived peer support. The total effects of compulsive Internet use and problem gambling on psychological well-being were negative. This study implies the significance of strengthening the knowledge about the impact of peer relationships among adolescents.