1. [Hemorrhagic dengue fever after trip to Malaysia].
- Author
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Hafner C, Koellner K, Vogt T, Landthaler M, and Szeimies RM
- Subjects
- Adult, Antibodies, Viral blood, Dengue Virus immunology, Diagnosis, Differential, Germany, Humans, Immunoglobulin G blood, Immunoglobulin M blood, Malaysia, Male, Severe Dengue immunology, Severe Dengue pathology, Skin pathology, Severe Dengue diagnosis, Travel
- Abstract
A 39-year-old patient developed a disseminated rash with scattered petechiae, fever, malaise and arthralgia after a trip to Malaysia. The patient displayed increasing dengue IgG titers and borderline dengue IgM titers. Dengue fever with a hemorrhagic course is a rare condition in adult patients. Patients who have previously had dengue fever and retained non-neutralizing heterotypic antibodies are more likely to develop this complication via the phenomenon of antibody-dependent enhancement.
- Published
- 2006
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