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• The design, production and improvement of ITER/DEMO radiation tolerance materials (low/reduced activation steels, ODS steels, Cu-based materials and HEAs) • The development of a triple line ion-accelerator facility for material irradiation at ITER/DEMO relevant irradiation dose and dose rates. • The construction of experimental PbLi loops for i) testing steels protecting barriers against corrosion and tritium permeation, and ii) validation of prototypes for dynamic tritium extraction systems. • Simultaneous or sequential material irradiation experiments with lasers and heavy ions, ion beam analysis of materials and multi-scale computations, to study the damage processes of materials under conditions of strong irradiation and concentrated particle flow. • To contribute to the technological development of DONES and ITER/DEMO, by i) defining specific procedures for remote handling and safety, and ii) optimizing the computational neutronics tools for the design of components and systems. With the objective of contributing to the European development of materials, technologies and facilities for the demonstration of the thermonuclear fusion, the construction of the unique TechnoFusión facility was planned in 2009. The TechnoFusión consortium, formed by selected Spanish research groups and laboratories located in Madrid, has jointly advanced in the search for solutions to the remaining technological issues of nuclear fusion by magnetic and inertial confinement. In addition, the foundation of the TechnoFusión partnership has been essential to create a network of collaborations, and also to expand and specialize human resources, by training scientists and technical staff in the use of high-tech tools. Supported by the TechnoFusión_Comunidad Madrid (III) regional programme, the consortium is focused on providing support for the construction of medium--sized, relevant facilities in Madrid (Spain). Regarding magnetic and inertial fusion issues, the programme is structured in several key experiments and infrastructures, which combine the development of materials, of cutting-edge technologies and the construction of associated facilities, with the progress in simulation and application of computational neutronics: [ABSTRACT FROM AUTHOR]

The implantation and irradiation beamline of the Tandem ion accelerator of the Centro de Micro Análisis de Materiales (CMAM), in Madrid, has been recently completed with a beam sweep and monitoring system, and a cryostat/furnace. These new implementations convert the beamline into a versatile tool to implant ions, between H and Au2, in different materials with precise control of the sample temperature, which may be varied between −180°C and 600°C. The size of the swept area on target may be as large as 10 ×10cm2. The implantation chamber also allows carrying out in situ or/and on line analyses during the irradiations by means of advanced optical measurements, as well as ion beam analyses (IBA). These advancements can be employed in novel applications such as the fabrication of optical waveguides and irradiation tests of structural and functional materials for future fusion reactors. The results of beam tests and first experiments are shown. [ABSTRACT FROM AUTHOR]

Propofol affects human platelet aggregation (Aoki et al. 1998). The use of anaesthetics that alter aggregation in experimental animals may modify the results of experimental work involving platelets. This study investigated the effects of an IV dose of propofol on platelet aggregation in pigs. [ABSTRACT FROM AUTHOR]